686776-95-4

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 536-74-3 phenylacetylene 

Downstream Products

• 25023-37-4 (E)-1-(3-bromophenyl)-3-phenylprop-2-en-1-one 
• 346685-14-1 2-(3-bromophenyl)-4-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepine 
• 1315379-39-5 dimethyl 4-bromo-1-oxo-3-phenyl-1H-inden-2-ylphosphonate 
• 1315379-33-9 dimethyl 6-bromo-1-oxo-3-phenyl-1H-inden-2-ylphosphonate 
• 928843-00-9 2-(3-bromophenyl)-2-(2-phenylethynyl)-1,3-dithiolane 
• 53692-59-4 1-(3-bromophenyl)-3-phenylprop-2-yn-1-one 

Relevant academic research and scientific papers

Synthesis of phosphonylated and thiolated indenones by manganese(III)- mediated addition of phosphorus- and sulfur-centered radicals to 1,3-diarylpropynones

Phosphorus- or sulfur-centered radicals generated from the reaction of manganese(III) acetate with dialkyl phosphonates or arylthiols undergo selective additions to conjugated alkynes followed by cyclization and rearomatization to afford 2-phosphonyl- or

Organoborane-catalyzed selective 1,2-reduction of alkynones with hydride transfer: Synthesis of benzyl alkynes

Benzyl alkynes are important organic building blocks in organic synthesis. We report herein a B(C6F5)3-catalyzed site-selective 1,2-reduction of readily available alkynones to access benzyl alkyne derivatives. Under the de

Modulation of silver-titania nanoparticles on polymethylhydrosiloxane-based semi-interpenetrating networks for catalytic alkynylation of trifluoromethyl ketones and aromatic aldehydes in water

In this work, we have developed a new approach to monodispersed hybrid Ag@TiO2 nanocomposites using a titanium-promoted cross-linking reduction in the Si-H functional material, polymethylhydrosiloxane (PMHS)-based semi-interpenetrating networks

Synthesis of quinazoline based chiral ligands and application in the enantioselective addition of phenylacetylene to aldehydes

Five novel 4-phenylquinazolinols were synthesised in three steps. Their application as ligands in the titanium tetraisopropoxide promoted catalytic enantioselective addition of phenylacetylene to a variety of aldehydes gave propargylic alcohols. Under the

Au(PPh3)Cl-AgSbF6-catalyzed rearrangement of propargylic 1,3-dithianes: Formation of 8-membered 1,3-bisthio-substituted cyclic allenes

Au(PPh3)Cl-AgSbF6-catalyzed rearrangement of propargylic 1,3-dithiane leads to the formation of 8-membered dithio-substituted cyclic allenes, which are remarkably stable. The Royal Society of Chemistry 2009.

Me3Ga-mediated alkynylation of aldehydes

The trimethylgallium reagent was found to promote the addition of phenylacetylene to various aromatic and aliphatic aldehydes. This reaction was efficiently carried out in anhydrous CH2Cl2 at room temperature under mild conditions an

Au-catalyzed reaction of propargylic sulfides and dithioacetals

(Chemical Equation Presented) Propargylic sulfides and dithioacetals are found to undergo similar transformations as propargylic carboxylates when catalyzed by AuCl or AuCl3, affording indene derivatives through pentannulation of aromatic rings

Me2Zn-mediated addition of acetylenes to aldehydes and ketones

Contrary to expectations, commercially available 2 M Me2Zn in toluene is able to promote the addition of phenylacetylene to aldehydes and ketones. This reactivity is determined by a new, unprecedented mechanism, which involves activation of the zinc reagent via coordination with carbonyl substrates that behave "ligand like". Broad scope, high tolerance to functional groups, and a simple procedure make this new method highly interesting for the synthetic chemist.