68690-18-6

Basic information

• Product Name: (2E,4E)-methyl 7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxohepta-2,4-dienoate
• Synonyms: (2E,4E)-methyl 7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxohepta-2,4-dienoate
• CAS NO: 68690-18-6
• Molecular Weight: 301.386
• Mol File: 68690-18-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2E,4E)-methyl 7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxohepta-2,4-dienoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,4E)-methyl 7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxohepta-2,4-dienoate(68690-18-6)
• EPA Substance Registry System: (2E,4E)-methyl 7-(4-(dimethylamino)phenyl)-4,6-dimethyl-7-oxohepta-2,4-dienoate(68690-18-6)

Safety Data

• Hazardous Substances Data: 68690-18-6(Hazardous Substances Data)

Upstream product

• 26672-58-2 1-(4-dimethylaminophenyl)propan-1-one 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 82946-80-3 1-(4-N,N'-dimethylaminophenyl)-1-propanol 
• 951161-60-7 (E)-((3-bromo-2-methylallyl)oxy)(tert-butyl)dimethylsilane 
• 7646-85-7 zinc(II) chloride 
• 1312938-51-4 (2E,4E)-methyl 5-bromo-4-methylpenta-2,4-dienoate 

Relevant articles and documents

SYNTHESIS OF HDAC INHIBITORS: TRICHOSTATIN A AND ANALOGUES

Embodiments herein relate to histone deacetylaces (HDACs) and HDAC inhibitors, such as trichostatin A (TSA) and TSA analogues. Embodiments provide simple methods of synthesizing TSA and TSA analogues. These methods provide routes of synthesis of TSA and TSA analogues that enable the production of the HDAC inhibitors at lower cost and in greater quantities than previously were available.

Trichostatin C, a glucopyranosyl hydroxamate

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