68702-73-8Relevant academic research and scientific papers
Synthetic routes to campesterol and dihydrobrassicasterol: A first reported synthesis of the key phytosterol dihydrobrassicasterol
O'Connell,O'Callaghan,O'Brien,Maguire,McCarthy
, p. 4995 - 5004 (2012/08/28)
Phytosterols are increasingly used as health supplements in functional foods and are associated with having both positive and negative effects on health. Given this disparity, an investigation of their full individual biological profile is imperative in order to assure food safety. This paper describes the de novo synthesis of pure phytosterols in multigram scale and we report the first synthesis of the key phytosterol dihydrobrassicasterol along with a comparison of routes to campesterol. A detailed spectroscopic analysis is included with full assignment of the 13C NMR spectroscopic data of both compounds, mixtures and their precursors leading to the potential use of NMR spectroscopy as a tool for analysis of these sterol mixtures.
Phosphorus ylide chemistry investigated for dihydrotachysterol2 metabolite side-chain synthesis: The Wittig approach
Hanekamp,Rookhuizen Boer,Bos,Brandsma
, p. 5151 - 5162 (2007/10/02)
The behaviour of the γ-oxido ylide of R-(3-hydroxy-2,3-dimethylbutyl)triphenylphosphonium iodide 4, to be used in the 25-hydroxylated DHT2 side-chain synthesis, was studied. The synthesis of the chiral phosponium salt 4 was done in an overall y
