68703-52-6

Upstream product

• 68703-54-8 2,3,4,6-tetra-O-acetyl-1-S-trityl-1-thio-β-D-glucopyranose 
• 19879-84-6 tetraacetyl thioglucose 
• 76-83-5 trityl chloride 

Downstream Products

• 857657-42-2 triphenylmethyl 2,3,4,6-tetra-O-pivaloyl-1-thio-β-D-glucopyranoside 
• 857657-43-3 triphenylmethyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside 
• 857657-51-3 triphenylmethyl 4,6-O-benzylidene-1-thio-β-D-glucopyranoside 
• 857892-35-4 triphenylmethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside 
• 72174-24-4 (2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-thiol 
• 247257-17-6 (2R,3R,4S,5R,6S)-2-((benzoyloxy)methyl)-6-mercaptotetrahydro-2H-pyran-3,4,5-triyl tribenzoate 
• 857657-62-6 2-bromo-2-methylpropyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside 
• 857657-59-1 2-hydroxy-2-methylpropyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside 

Relevant academic research and scientific papers

2-Haloethyl 1-thioglycosides as new tools in glycoside syntheses. Part 1: Preparation, characteristics, general reactions

2-Haloethyl 1-thioglycosides are excellent leaving groups when the 2-haloethyl function is activated with silver salts or Lewis acids. These thioglycosides can be synthesized on the original Cerny route or for better compatibility with the needs of a more complex glycoside synthesis, in stepwise procedures via 2-(2-tetrahydropyran-2-yloxy)ethyl glycosides or trityl 1-thioglycosides. The initial step in glycosidation reaction presumably proceeds via a thiiranium ion, which is responsible for their increased reactivity compared with normal thioethers as leaving groups in glycoside syntheses. Basic features of this new system with respect to reactivity and selectivity in disaccharide syntheses are described.

Trialkylphosphinegold(I)-lower alkyl carbamoyl glucopyranosides

The compounds are trialkylphosphinegold(I)2,3,4,6-tetra-O-(N-loweralkylcarbamoyl)-1-thio-β-D-glucopyranosides which have antiarthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis.

Tri-substituted phosphinegold(I) 1-thio-β-D-glucopyranosides

The compounds are tri-substituted phosphinegold(I) 1-thio-β-D-glucopyranosides which have antiarthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis. Of the three substituents on the phosphine one is optionally substituted phenyl and the others are lower alkyl or lower alkoxy.