68746-11-2

Upstream product

• 14673-56-4 acetone-4-phenylthiosemicarbazone 
• 1484-50-0 desyl bromide 
• 753011-88-0 C₂₄H₂₁N₃S 

Downstream Products

• 1470070-98-4 2-benzylidenehydrazono-3,4,5-triphenyl-2,3-dihydro-1,3-thiazole 
• 1470070-99-5 C₂₈H₂₀N₄O₂S 
• 143541-59-7 5-Methyl-2-phenyl-4-{[3,4,5-triphenyl-3H-thiazol-(2E)-ylidene]-hydrazono}-2,4-dihydro-pyrazol-3-one 

Relevant academic research and scientific papers

Cyclocondensations of substituted thiosemicarbazides with 2-bromo-1,2-diphenylethan-1-one

The cyclocondensation of 4-methylthiosemicarbazide with 2-bromo-1,2-diphenylethan-1-one in ethanol afforded isomeric 2-methylamino-5,6-diphenyl-6H-3,4-thiadiazine and 2-hydrazono-3- methyl-4,5-diphenyl-2,3-dihydro-1,3-thiazole. A pyrazole was obtained by cyclocondensation and subsequent desulfurization of the thiadiazine when the reaction was carried out in concentrated hydrochloric acid. A chemical proof of the structures has been provided. The product distribution of the cyclizations strongly depends on the substitution pattern of the starting materials, and the cyclizations of methylthiosemicarbazide with 2-bromo-1,2-diphenylethan-1-one behaved considerably different from that of the analogous reactions of α-bromoacetophenone.