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Phi-dihydrothebaine is a synthetically derived chemical compound, classified as a semi-synthetic opioid analgesic. It is a key intermediate in the production of several potent opioids, including oxycodone, oxymorphone, and hydrocodone. Derived from thebaine, a naturally occurring alkaloid found in the opium poppy plant, phi-dihydrothebaine is used in pharmaceutical manufacturing processes to create various pain-relieving medications. Due to its potential for abuse and its role in the synthesis of illicit drugs, the production and distribution of phi-dihydrothebaine are strictly regulated in many countries.

6878-93-9

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6878-93-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6878-93-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,7 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6878-93:
(6*6)+(5*8)+(4*7)+(3*8)+(2*9)+(1*3)=149
149 % 10 = 9
So 6878-93-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H23NO3/c1-20-9-8-19-11-13(22-2)5-6-14(19)15(20)10-12-4-7-16(23-3)18(21)17(12)19/h4,6-7,11,15,21H,5,8-10H2,1-3H3/t15-,19+/m0/s1

6878-93-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Morphinan-4-ol,5,6,8,14-tetradehydro-3,6-dimethoxy-17-methyl

1.2 Other means of identification

Product number -
Other names 5,6,8,14-Tetradehydro-3,6-dimethoxy-17-methylmorphinan-4-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6878-93-9 SDS

6878-93-9Upstream product

6878-93-9Relevant academic research and scientific papers

Synthesis of β-dihydrothebaine

Razdan,Portlock,Dalzell,Malmberg

, p. 3604 - 3606 (1978)

The authors have found that the reaction of thebaine with K/liquid NH3 gives a 1:1 mixture of 2 and 3 in 95% yield. It was also observed that treatment of phi-DHT (3) with K/liquid NH3 in the presence of a catalytic amount of Fe(NO3)3 x 9H2O7 gave a 1:1 mixture of 2 and 3 in 79% yield. These results suggest that an intermediate dianion 5 is formed which is protonated either at C5 or C7.

Improved synthesis of dihydrothebainone and its 14 β-epimer

Davidson,Gregg

, p. 547 - 558 (2007/10/03)

An improved synthesis for the preparation of diastereomerically pure dihydrothebainone (1) from thebaine (3) is reported. A 41% overall yield was realized over three steps via direct transformation of dihydrothebaine-Φ (4) to thebainone-A (6) with 6N HCl.

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