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6880-91-7

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6880-91-7 Usage

Description

Dihydrochelerythrine is a benzophenanthridine alkaloid that has been found in Bocconia arborea and has diverse biological activities. It is active against S. aureus, S. faecalis, and C. albicans (MIC = 1.87 μg/ml for all). Dihydrochelerythrine inhibits secretion of the hepatitis B virus (HBV) antigens HBsAg and HBeAg from HepG2 2.2.15 cells (IC50s = <0.05 μM for both). It is cytotoxic to HCT8, BGC-823, and A2780 cancer cells (IC50s = 1.4, 0.4, and 3.5 μM, respectively).

Uses

Dihydrochelerythrine is synthesized as a potential G-quadrulpex DNA stabilizing agent. It is used in phamacokinetic study of chelerythrine metabolites in agro-products.

Check Digit Verification of cas no

The CAS Registry Mumber 6880-91-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,8 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6880-91:
(6*6)+(5*8)+(4*8)+(3*0)+(2*9)+(1*1)=127
127 % 10 = 7
So 6880-91-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H19NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-9H,10-11H2,1-3H3

6880-91-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine

1.2 Other means of identification

Product number -
Other names Dihydrochelerythrine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6880-91-7 SDS

6880-91-7Relevant articles and documents

Chemical Transformation of Protoberberines. Part 9. A Biomimetic Synthesis of Oxychelerythrine, Dihydrochelerythrine, and Chelerythrine from Berberine

Hanaoka, Miyoji,Motonishi, Toshio,Mukai, Chisato

, p. 2253 - 2256 (2007/10/02)

Fully aromatised benzophenanthridine alkaloids, oxychelerythrine (4), dihydrochelerythrine (9), and chelerythrine (10) have been efficiently synthesized from berberine (1), a protoberberine alkaloid, via oxidative C(6)-N bond cleavage, followed by recyclisation betwen the C-6 and C-13 positions of (1) by a biogenetic process.

Biosynthesis of benzo[c]phenanthridine alkaloids sanguinarine, chelirubine and macarpine

Takao,Kamigauchi,Okada

, p. 473 - 484 (2007/10/02)

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