Dihydrochelerythrine

Base Information

Chemical Name:Dihydrochelerythrine
CAS No.:6880-91-7
Molecular Formula:C21H19NO4
Molecular Weight:349.386
Hs Code.:2933990090
European Community (EC) Number:807-650-1
DSSTox Substance ID:DTXSID70218913
Nikkaji Number:J391.781I
Wikidata:Q72464723
Metabolomics Workbench ID:133588
ChEMBL ID:CHEMBL400359
Mol file:6880-91-7.mol

Synonyms:dihydrochelerythrine

Suppliers and Price of Dihydrochelerythrine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dihydrochelerythrine
1mg
$ 55.00

Medical Isotopes, Inc.
Dihydrochelerythrine 98%
20 mg
$ 667.00

JR MediChem
Dihydrochelerythrine(NewProduct) 98%(HPLC)
10mg
$ 248.00

Crysdot
Dihydrochelerythrine 98+%
5mg
$ 135.00

ChemScene
Dihydrochelerythrine 99.39%
10mg
$ 288.00

ChemScene
Dihydrochelerythrine 99.39%
5mg
$ 180.00

Cayman Chemical
Dihydrochelerythrine
5mg
$ 151.00

Cayman Chemical
Dihydrochelerythrine
10mg
$ 280.00

Cayman Chemical
Dihydrochelerythrine
25mg
$ 450.00

Cayman Chemical
Dihydrochelerythrine
1mg
$ 41.00

Total 37 raw suppliers

Chemical Property of Dihydrochelerythrine

Chemical Property:

Vapor Pressure:7.92E-13mmHg at 25°C
Melting Point:164-165 °C
Boiling Point:565.9°Cat760mmHg
PKA:2.36±0.20(Predicted)
Flash Point:171.6°C
PSA：40.16000
Density:1.291g/cm³
LogP:4.26750
Storage Temp.:2-8°C
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:349.13140809
Heavy Atom Count:26
Complexity:516

Purity/Quality:

≥98% ^*data from raw suppliers

Dihydrochelerythrine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5
Description Dihydrochelerythrine is a benzophenanthridine alkaloid that has been found in Bocconia arborea and has diverse biological activities. It is active against S. aureus, S. faecalis, and C. albicans (MIC = 1.87 μg/ml for all). Dihydrochelerythrine inhibits secretion of the hepatitis B virus (HBV) antigens HBsAg and HBeAg from HepG2 2.2.15 cells (IC50s = <0.05 μM for both). It is cytotoxic to HCT8, BGC-823, and A2780 cancer cells (IC50s = 1.4, 0.4, and 3.5 μM, respectively).
Uses Dihydrochelerythrine is synthesized as a potential G-quadrulpex DNA stabilizing agent. It is used in phamacokinetic study of chelerythrine metabolites in agro-products.

Technology Process of Dihydrochelerythrine

There total 3 articles about Dihydrochelerythrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 4070-42-2
6-hydroxy-5,6-dihydrochelerythrine

: 6880-91-7
12,13-dihydrochelerythrine

Guidance literature:: With sodium tetrahydroborate; In methanol; for 0.5h; Ambient temperature;

Reference yield: 1.4%

: 16211-68-0,24031-76-3,37791-14-3,57089-29-9,59895-76-0,85888-53-5,85888-54-6
(+/-)-cis-N-methyl-7,8,13,13a-tetrahydroberberinium chloride

: 6880-91-7
12,13-dihydrochelerythrine

: 485-91-6,24240-04-8
allocryptopine

Guidance literature:: In water; at 24 ℃; for 192h; incorporation experiment on Macleaya cordata in Murashige and Skoog's medium;
DOI:10.1002/hlca.19830660208

Reference yield: 0.4%

: 522-97-4,2086-96-6,5096-57-1,29074-38-2
canadine

: 6880-91-7
12,13-dihydrochelerythrine

: 4263-84-7
berberine iodide

: 485-91-6,24240-04-8
allocryptopine

Guidance literature:: In water; at 24 ℃; for 144h; incorporation experiment on Macleaya cordata in Murashige and Skoog's medium;
DOI:10.1002/hlca.19830660208