688021-88-7

Basic information

• Product Name: (S)-SN-1,2-DIOCTANOYL-3-BENZYLGLYCEROL
• Synonyms: (S)-SN-1,2-DIOCTANOYL-3-BENZYLGLYCEROL;Octanoic Acid 1,1'-[(1S)-1-[(PhenylMethoxy)Methyl]-1,2-ethanediyl] Ester
• CAS NO: 688021-88-7
• Molecular Formula: C₂₆H₄₂O₅
• Molecular Weight: 434.61
• Product Categories: Chiral Reagents;Fatty Acid Derivatives & Lipids;Glycerols;Protein Kinase Inhibitors and Activators
• Mol File: 688021-88-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane, Ether, Ethyl Acetate, Methanol
• CAS DataBase Reference: (S)-SN-1,2-DIOCTANOYL-3-BENZYLGLYCEROL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-SN-1,2-DIOCTANOYL-3-BENZYLGLYCEROL(688021-88-7)
• EPA Substance Registry System: (S)-SN-1,2-DIOCTANOYL-3-BENZYLGLYCEROL(688021-88-7)

Safety Data

• Hazardous Substances Data: 688021-88-7(Hazardous Substances Data)

Usage

Chemical Properties

Clear Colourless Oil

Uses

(S)-sn-1,2-Dioctanoyl-3-benzylglycerol (cas# 688021-88-7) is a compound useful in organic synthesis.

Upstream product

• 56552-80-8 (R)-3-benzyloxy-1,2-propanediol 
• 111-64-8 n-octanoic acid chloride 

Downstream Products

• 905911-92-4 2-O-benzyl-1,3-bis[(1,2-di-O-octanoyl-sn-glycero-3)-phosphoryl]glycerol di(2-cyanoethyl) ester 
• 60514-48-9 1,2-dioctanoyl-sn-glycerol 

Relevant articles and documents

A synthesis of dioctanoyl phosphatidylinositol

A synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter than the naturally occurring lipid chains, providing the molecule with enhanced water solubility.

Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands

Short-chain phosphatidic acid derivatives, dioctanoyl glycerol pyrophosphate (DGPP 8:0, 1) and phosphatidic acid 8:0 (PA 8:0, 2), were previously identified as subtype-selective LPA1 and LPA3 receptor antagonists. Recently, we report