688024-60-4Relevant academic research and scientific papers
FACILITATED FORWARD CHEMICAL GENETICS USING TAGGED TRIAZINE LIBRARY
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Page 19; 28, (2010/02/09)
A novel tagged triazine library is provided in which three building blocks are prepared separately and assembled orthogonally to yield 1536 highly pure compounds. Each library compound contains a variety of a triethyleneglycol (TG) linker t one of the div
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening
Khersonsky, Sonya M.,Jung, Da-Woon,Kang, Tae-Wook,Walsh, Daniel P.,Moon, Ho-Sang,Jo, Hakryul,Jacobson, Eric M.,Shetty, Vivekananda,Neubert, Thomas A.,Chang, Young-Tae
, p. 11804 - 11805 (2007/10/03)
An improved forward chemical genetics approach was successfully demonstrated using a tagged library concept. A small-molecule triazine library with linkers was used to screen for brain/eye developmental phenotypes in a zebrafish embryo system. This approa
