688298-26-2Relevant academic research and scientific papers
Ring expansion of 5- to 6-member zirconacycles by carbenoid insertion
Dixon, Sally,Fillery, Shaun M.,Kasatkin, Aleksandra,Norton, David,Thomas, Emma,Whitby, Richard J.
, p. 1401 - 1416 (2004)
A wide range of carbenoids (1-lithio-1-halo species), including those with α-SiR3, OEt, SPh, SO2Ph, P(O)(OEt)2, and CN substituents, insert into 5-member zirconacycles (saturated and unsaturated, mono- and bi-cyclic) to afford functionalized 6-member zirconacycles. 1-Lithio-1-haloalkenes insert to afford 6-member zirconacycles with an alkylidene substituent next to the metal. Unexpected double insertion of some carbenoids, and evidence for endocylic β-hydride transfer processes provide additional mechanistic interest.
The regiochemistry of zirconacycle elaboration
Thomas, Emma,Dixon, Sally,Whitby, Richard J.
, p. 11686 - 11701 (2008/03/14)
The regioselectivity of insertion of carbenoids into a variety of unsymmetrical zirconacyclopentanes is reported. For comparison the regioselectivities of isonitrile insertion and protonation have also been determined.
