688349-21-5

Basic information

• Product Name: 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione
• Synonyms: 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione
• CAS NO: 688349-21-5
• Molecular Weight: 541.624
• Mol File: 688349-21-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione(688349-21-5)
• EPA Substance Registry System: 2-[(S)-1-((3R,4aS,5R,7aS)-5-Benzenesulfonyl-6-methylene-1-oxo-octahydro-cyclopenta[c]pyran-3-yl)-2-phenyl-ethyl]-isoindole-1,3-dione(688349-21-5)

Safety Data

• Hazardous Substances Data: 688349-21-5(Hazardous Substances Data)

Upstream product

• 688349-14-6 (5R,6S)-6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-5-hydroxy-7-phenyl-hept-2-ynoic acid methyl ester 
• 688349-11-3 2-((1S,2R)-1-Benzyl-2-hydroxy-pent-4-ynyl)-isoindole-1,3-dione 
• 136465-80-0 2(S)-[2-phenyl-1(S)-phthalimidoethyl]oxirane 
• 129800-98-2 2-(bromomethyl)-3-(phenylsulfonyl)-1-propene 
• 688349-15-7 2-[(S)-1-((R)-6-Oxo-3,6-dihydro-2H-pyran-2-yl)-2-phenyl-ethyl]-isoindole-1,3-dione 

Relevant articles and documents

HIV protease inhibitors part 2: [3+2] Cycloaddition, isomerization; and ring expansion en route to 4,5-substituted cyclohexenones

4,5-Substituted cyclohexanone 10 and its derivatives are carbocyclic analogues of Indinavir 3 and are expected to have antiviral activity. Early attempts to obtain these compounds via a diastereoselective [3+2] cycloaddition between 19 and 14 failed due t