688362-44-9

Basic information

• Product Name: (4S,5R)-5-({[1-(tert-butyl)-1,1-diphenylsilyl]-oxy}-methyl)-2,4-diphenyl-1,3-oxazoline
• Synonyms: (4S,5R)-5-({[1-(tert-butyl)-1,1-diphenylsilyl]-oxy}-methyl)-2,4-diphenyl-1,3-oxazoline
• CAS NO: 688362-44-9
• Molecular Weight: 491.705
• Mol File: 688362-44-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5R)-5-({[1-(tert-butyl)-1,1-diphenylsilyl]-oxy}-methyl)-2,4-diphenyl-1,3-oxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-5-({[1-(tert-butyl)-1,1-diphenylsilyl]-oxy}-methyl)-2,4-diphenyl-1,3-oxazoline(688362-44-9)
• EPA Substance Registry System: (4S,5R)-5-({[1-(tert-butyl)-1,1-diphenylsilyl]-oxy}-methyl)-2,4-diphenyl-1,3-oxazoline(688362-44-9)

Safety Data

• Hazardous Substances Data: 688362-44-9(Hazardous Substances Data)

Upstream product

• 688362-43-8 (S)-N-1-(3-[(1-tert-butyl)-1,1-diphenylsilyl]oxy-2-oxo-1-phenylpropyl)benzamide 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 688362-79-0 (1S,2S)-N-1-(3-{[(1-tert-butyl)-1,1-diphenylsilyl]oxy}-2-hydroxy-1-phenylpropyl)benzamide 

Downstream Products

• 158722-22-6 (4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid 
• 146848-91-1 (4S,5R)-2,4-diphenyl-2-oxazoline-5-carboxylic acid methyl ester 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 688362-45-0 (4S,5R)-[2,4-diphenyl-(5-hydroxymethyl)]-1,3-oxazoline 

Relevant articles and documents

Enantioselective synthesis of 1-aryl-2-propenylamines: A new approach to a stereoselective synthesis of the Taxol side chain

A variety of substituted 1-aryl-2-propenylamines of high enantiomeric purity were prepared via lipase-catalysed resolution of the corresponding racemates. (R)-1-Phenyl-2-propenylamine was further synthesised into (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoic acid methyl ester, the side chain of Taxol.