688797-19-5Relevant academic research and scientific papers
Asymmetric Synthesis of Novel Thioiso Dideoxynucleosides with Exocyclic Methylene as Potential Antiviral Agents
Gunaga, Prashantha,Baba, Masanori,Jeong, Lak Shin
, p. 3208 - 3211 (2004)
Novel thioiso pyrimidine and purine nucleosides substituted with exocyclic methylene have been synthesized, starting from D-xylose. The glycosyl donor 14 was synthesized from D-xylose, using cyclization of dimesylate 10 with sodium sulfide as a key step.
Stereoselective synthesis of novel thioiso dideoxy nucleosides with exocyclic methylene as potential antiviral agents
Gunaga, Prashantha,Kim, Hea Ok,Kim, Hyun Ji,Chun, Moon Woo,Jeong, Lak Shin
, p. 1115 - 1117 (2008/02/01)
Novel thioiso pyrimidine and purine nucleosides substituted with exocyclic methylene have been synthesized, starting from D-xylose. Cyclization of the dimesylate to the 4-thiosugar 6a proceeded in pure SN2 reaction in the presence of allylic fu
