688809-44-1

Upstream product

• 603-85-0 2-Amino-3-nitrophenol 
• 639084-14-3 3-tert-butyldimethylsiloxy-2-amino-1-nitrobenzene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 688809-45-2 C₁₂H₁₉BrN₂O₃Si 

Downstream Products

• 688808-13-1 C₂₂H₂₄BrFN₂O₄Si 

Relevant academic research and scientific papers

NOVEL BICYCLIC BROMODOMAIN INHIBITORS

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

NOVEL QUINOXALINE DERIVATIVES

A quinoxalinone derivative of the formula (I): or a pharmaceutically acceptable salt or ester thereof, wherein; ???X is NH, S or the like; ???Y is O or the like; ???the partial structure is, for example, the formula: ???B1, B2, ....., Bn-1 and Bn, (in which n is 4 , 5 or 6) are each independently CH, N or the like; ???B'1, B'2, ....., B'n-1 and B'n (in which n is 4, 5 or 6) are each independently hydrogen or the like; and ???R is hydrogen, lower alkyl or the like.