68889-66-7

Basic information

• Product Name: (Z)-benzylidene-((S)-1-phenyl-ethyl)-amine oxide
• CAS NO: 68889-66-7
• Molecular Weight: 225.29
• Mol File: 68889-66-7.mol

Chemical Properties

• CAS DataBase Reference: (Z)-benzylidene-((S)-1-phenyl-ethyl)-amine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-benzylidene-((S)-1-phenyl-ethyl)-amine oxide(68889-66-7)
• EPA Substance Registry System: (Z)-benzylidene-((S)-1-phenyl-ethyl)-amine oxide(68889-66-7)

Safety Data

• Hazardous Substances Data: 68889-66-7(Hazardous Substances Data)

Upstream product

• 53933-47-4 N-((1S)-1-phenylethyl)hydroxylamine 
• 100-52-7 benzaldehyde 
• 78798-33-1 (S)-N-hydroxy-α-methyl-benzenemethanamine ethanedioate 
• 611-73-4 Benzoylformic acid 
• 17480-69-2 (S)-N-benzyl-1-phenylethylamine 

Downstream Products

• 64270-70-8 (S)-3,4-diphenyl-2-((S)-1-phenyl-ethyl)-[1,2,4]oxadiazolidin-5-one 
• 64478-21-3 (R)-3,4-diphenyl-2-((S)-1-phenyl-ethyl)-[1,2,4]oxadiazolidin-5-one 
• 64270-68-4 (5R)-3t-phenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine-5r-carboxylic acid methyl ester 
• 64270-62-8 (5S)-3c-phenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine-5r-carboxylic acid methyl ester 
• 64270-61-7 (5S)-5-methyl-3c-phenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine-5r-carboxylic acid methyl ester 
• 64270-60-6 (3R)-3r,5c-diphenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine 
• 64282-93-5 (3S)-3r,5c-diphenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine 
• 64270-67-3 (3R)-3r,5t-diphenyl-2-((S)-1-phenyl-ethyl)-isoxazolidine 

Relevant articles and documents

One-flask transformation of secondary amines to nitrones by oxidation with hydrogen peroxide mediated by triscetylpyridinium tetrakis oxodiperoxotungsto-phosphate (PCWP). Some mechanistic considerations

Acyclic and cyclic secondary amines are oxidized to nitrones by H2O2/PCWP system in water/chloroform under phase transfer catalysis conditions. The different acidities of the protons of the carbon atoms α to the nitrogen might be responsible for the identity and ot the stereochemistry of the formed nitrone. The presence of an aromatic ring such as benzene directly linked to the nitrogen represents a limitation, since in this case many oxidation products are observed. As far as the mechanistic aspects are concerned, it is suggested that the oxidation process might be started by a nucleophilic attack of the amine to the peroxidic oxygens of the peroxometal complex or by a single electron transfer from the amine to the oxidant.