689-11-2

Basic information

• Product Name: N-sec-Butylurea
• Synonyms: secondarybutylurea;Urea, sec-butyl-;1-sec-Butylurea;Nsc27458;Urea, (1-methylpropyl)-;N-(SEC-BUTYL)UREA;N-(1-METHYLPROPYL)UREA;TIMTEC-BB SBB008605
• CAS NO: 689-11-2
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116.16
• EINECS: 211-709-1
• Mol File: 689-11-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 165-166 °C
• Boiling Point: 217.23°C (rough estimate)
• Flash Point: 57.5oC
• Appearance: /
• Density: 1.0551 (rough estimate)
• Vapor Pressure: 1.4mmHg at 25°C
• Refractive Index: 1.4496 (estimate)
• PKA: 14.40±0.46(Predicted)
• CAS DataBase Reference: N-sec-Butylurea(CAS DataBase Reference)
• NIST Chemistry Reference: N-sec-Butylurea(689-11-2)
• EPA Substance Registry System: N-sec-Butylurea(689-11-2)

Safety Data

• Hazardous Substances Data: 689-11-2(Hazardous Substances Data)

Usage

General Description

N-sec-Butylurea is a chemical compound that falls under the category of urea compounds. It is an organic substance with its chemical formula as C7H16N2O. This powder-like substance is typically used in the industrial setting as a valuable intermediate in the production of various chemical products. It can be produced through the reaction of secondary butylamine with urea. Like other chemicals, it should be handled with care due to potential hazards such as skin or eye irritation and harmful effects if inhaled or ingested. Measures should also be taken to prevent its release into the environment as it could be harmful to aquatic life.

InChI:InChI=1/C5H12N2O/c1-3-4(2)7-5(6)8/h4H,3H2,1-2H3,(H3,6,7,8)/t4-/m1/s1

Upstream product

• 57-13-6 urea 
• 78-93-3 butanone 
• 13250-12-9 (R)-sec-butylamine 
• 4461-33-0 benzoyl isocyanate 
• 590-28-3 potassium cyanate 
• 33966-50-6 SEC-BUTYLAMINE 
• 1118-02-1 trimethylsilyl isocyanate 
• 556-89-8 nitrourea 

Downstream Products

• 92033-17-5 3-o-Toluoyl-1-i-butylharnstoff 

Relevant articles and documents

Deuterated benzylaminopyrimidine diketone derivative and application thereof

The invention discloses a deuterated benzylaminopyrimidine dione derivative and an application thereof, and a pharmaceutical composition containing the deuterated benzylaminopyrimidine dione derivative, and the deuterated benzylaminopyrimidine dione derivative and the pharmaceutical composition can be used for inhibiting the activity of myosin. The invention also relates to a method for preparingthe compound and the pharmaceutical composition, and an application of the compound and the pharmaceutical composition in treating hypertrophic cardiomyopathy and related heart diseases.

PYRIMIDINEDIONE COMPOUNDS AGAINST CARDIAC CONDITIONS

Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.