68900-49-2Relevant academic research and scientific papers
Sensitized Photooxygenation of Silyl Enol Ethers of Cyclic Ketones
Friedrich, Edgar,Lutz, Werner
, p. 1245 - 1263 (2007/10/02)
α,β-Unsaturated and α-hydroxy ketones are accessible in prototropic ene-reactions with singlet oxygen by sensitized photooxygenation of cyclic silyl enol ethers and subsequent reduction and solvolysis.In a competing silatropic ene-reaction α-silyloxyketones are formed.Formation of different products depends on ring size, configuration and substitution.At C-6 chirally substituted 2-cyclohexenones are synthesized for the first time by sensitized photooxygenation of chiral silyl enol ethers of optically active starting ketones.
