689260-01-3Relevant articles and documents
Antitumor agents. Part 232: Synthesis of cyclosulfite podophyllotoxin analogues as novel prototype antitumor agents
Xiao, Zhiyan,Han, Shiqing,Bastow, Kenneth F.,Lee, Kuo-Hsiung
, p. 1581 - 1584 (2004)
An 11,13-O,O′-cyclosulfite GL-331 analogue (7) was synthesized in six steps from podophyllotoxin and evaluated as a potential antitumor agent. Compound 7 was significantly cytotoxic against human tumor cell lines, but showed no inhibition against human DN