689260-64-8Relevant academic research and scientific papers
Efficient synthesis of 2'-O-cyanoethylated imidazole C-ribonucleoside phosphoramidite: A practical building block for probing the catalytic mechanism of ribozymes
Araki, Lisa,Zhao, Zheng-Yun,Lilley, David M. J.,Harusawa, Shinya
, p. 1861 - 1869 (2010)
A high-yielding synthetic route leading to new 2'-O-cyanoethylated imidazole C-ribonucleoside phosphoramidite (PA) 1 has been developed (41% overall yield in ten steps). This has resulted in a marked improvement of yield compared to unstable 2'-O-TBDMS PA
Synthesis of novel C4-linked imidazole ribonucleoside phosphoramidites for probing general acid and base catalysis in ribozyme
Araki, Lisa,Harusawa, Shinya,Yamaguchi, Maho,Yonezawa, Sumi,Taniguchi, Natsumi,Lilley, David M.J.,Zhao, Zheng-Yun,Kurihara, Takushi
, p. 11976 - 11985 (2007/10/03)
We describe the synthesis of novel C4-linked imidazole ribonucleoside phosphoramidite (PA) 1a by which the imidazole moiety is incorporated into VS ribozyme to study its role in general acid and base catalysis. Investigation of protecting groups for the i
Synthesis of C4-linked imidazole ribonucleoside phosphoramidite with pivaloyloxymethyl (POM) group
Araki, Lisa,Harusawa, Shinya,Yamaguchi, Maho,Yonezawa, Sumi,Taniguchi, Natsumi,Lilley, David M. J.,Zhao, Zheng-Yun,Kurihara, Takushi
, p. 2657 - 2661 (2007/10/03)
A novel C4-linked imidazole ribonucleoside phosphoramidite was designed and successfully synthesized starting from tribenzylribofuranosylimidazole. This phosphoramidite product enables incorporation of the imidazole moiety into an RNA sequence and hence a
