689284-03-5

Basic information

• Product Name: [2-((S)-2-Hydroxymethyl-4-oxo-pyrrolidine-1-carbonyl)-4,5-dimethoxy-phenyl]-carbamic acid 2,2,2-trichloro-ethyl ester
• Synonyms: [2-((S)-2-Hydroxymethyl-4-oxo-pyrrolidine-1-carbonyl)-4,5-dimethoxy-phenyl]-carbamic acid 2,2,2-trichloro-ethyl ester
• CAS NO: 689284-03-5
• Molecular Weight: 469.706
• Mol File: 689284-03-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-((S)-2-Hydroxymethyl-4-oxo-pyrrolidine-1-carbonyl)-4,5-dimethoxy-phenyl]-carbamic acid 2,2,2-trichloro-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-((S)-2-Hydroxymethyl-4-oxo-pyrrolidine-1-carbonyl)-4,5-dimethoxy-phenyl]-carbamic acid 2,2,2-trichloro-ethyl ester(689284-03-5)
• EPA Substance Registry System: [2-((S)-2-Hydroxymethyl-4-oxo-pyrrolidine-1-carbonyl)-4,5-dimethoxy-phenyl]-carbamic acid 2,2,2-trichloro-ethyl ester(689284-03-5)

Safety Data

• Hazardous Substances Data: 689284-03-5(Hazardous Substances Data)

Upstream product

• 29568-78-3 4,5-dimethoxy-2-nitrobenzoyl chloride 
• 260417-86-5 (5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-1-(4,5-dimethoxy-2-nitro-benzoyl)pyrrolidin-3-ol 
• 260417-87-6 (2S,4R)-N-(2-amino-4,5-dimethoxybenzoyl)-2-(tert-butyldimethylsilyloxymethyl)-4-hydroxypyrrolidine 
• 4998-07-6 4,5-dimethoxy-2-nitro-benzoic acid 
• 689284-02-4 {2-[2-(tert-butyl-dimethyl-silanyloxymethyl)-4-oxo-pyrrolidine-1-carbonyl]-4,5-dimethoxy-phenyl}-carbamic acid 2,2,2-trichloro-ethyl ester 
• 689284-01-3 {2-[(2S,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-hydroxy-pyrrolidine-1-carbonyl]-4,5-dimethoxy-phenyl}-carbamic acid 2,2,2-trichloro-ethyl ester 

Relevant articles and documents

A novel approach to the synthesis of cytotoxic C2-C3 unsaturated pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) with conjugated acrylyl C2-substituents

A concise synthesis of three novel C2-C3 unsaturated pyrrolo[2,1-c][1,4] benzodiazepine analogues (18-20) containing conjugated acrylyl C2-substituents is reported that utilises Heck coupling to install the C2-acrylyl side chains. These analogues possess