689303-73-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 689303-72-8 2-[2-(2-methoxycarbonyl-phenylcarbamoyl)-ethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 69610-41-9 Boc-L-Pro-H 
• 123751-11-1 tert-butyl (2S)-2-[(E)-3-methoxy-3-oxo-1-propenyl]-1-pyrrolidinecarboxylate 
• 65595-02-0 3-[(2S)-1-(tert-butoxycarbonyl)pyrrolidinyl]propanoic acid 
• 179685-62-2 (2S)-N-t-butoxycarbonyl-2-(3’-methoxy-3’-oxo-1-propyl)pyrrolidine 

Relevant academic research and scientific papers

A synthesis of the tetracyclic carboskeleton of isaindigotidione

An efficient synthesis of the unique indolizino[7,6-c]quinoline carboskeleton of isaindigotidione has been achieved. This strategy employed L-proline and isatin as the main building blocks in the construction of the framework. Four transformations occurred in a one-pot operation to furnish the tetracyclic nucleus.