68946-13-4Relevant academic research and scientific papers
The Regiospecific Synthesis of N-Substituted Pyrazoles. I. 1- and 2-Substituted Indenopyrazol-4(1H)-ones
Lemke, Thomas L.,Sawhney, Kailash N.
, p. 1335 - 1340 (2007/10/02)
The reaction of enaminoketones (2 or 5) of 2-acyl-1,3-indandiones with unsymmetrical hydrazines results in the regiospecific synthesis of 1,3- or 2,3-disubstituted indenopyrazol-4(1H)-ones (4 or 7).The synthesis of the enaminoketones (2 or 5) is accomplished by way of amine addition to the 2-acyl-1,3-indandiones 8a-c or by reduction of the indenoisoxazole 9.The structural assignment of the isomeric indenopyrazoles 4 and 7 is based upon 1H-nmr chemical shifts.
