85301-69-5

Upstream product

• 67-71-0 dimethylsulfone 
• 87885-97-0 3-phenylindeno<1,2-c>isoxazol-4-one 
• 22230-82-6 ((methyl-d3)sulfonyl)methane-d3 
• 1785-95-1 2-benzoyl-1,3-indanedione 
• 5381-33-9 2-benzylidene-indan-1,3-dione 

Downstream Products

• 69545-78-4 1-isopropyl-3-phenyl-1H-indeno[1,2-c]pyrazol-4-one 
• 85301-74-2 1-(2-Hydroxy-ethyl)-3-phenyl-1H-indeno[1,2-c]pyrazol-4-one 
• 85301-75-3 1-tert-Butyl-3-phenyl-1H-indeno[1,2-c]pyrazol-4-one 
• 60407-46-7 1,3-Diphenyl-1H-indeno[1,2-c]pyrazol-4-one 
• 68946-13-4 1-methyl-3-phenyl-1H-indeno[1,2-c]pyrazol-4-one 

Relevant academic research and scientific papers

Unusual Schmidt reaction of some 2-benzylideneindane-1,3-diones

Schmidt reaction of 2-benzylideneindane-1,3-diones (1) affords 2-(α-aminobenzylidene)indane-1,3-diones (2) and/or indeno[1,2-b]quinolin- 11-ones (3) in fairly good yields depending upon the nature of the substituent(s) in the benzylidene phenyl ring.

Ring Opening Reactions of Indenoisoxazolones

Nucleophilic attack of 8-substituted indenoisoxazol-7-ones (1) and 3-phenylindenoisoxazol-4-one (4) by dimethylsulfoxide or triphenylphosphine results in cleavage of the nitrogen-oxygen bond of the isoxazole ring leading to the formation of sulfoximides (2 and 5) and phosphazenes (3 and 8).

The Regiospecific Synthesis of N-Substituted Pyrazoles. I. 1- and 2-Substituted Indenopyrazol-4(1H)-ones

The reaction of enaminoketones (2 or 5) of 2-acyl-1,3-indandiones with unsymmetrical hydrazines results in the regiospecific synthesis of 1,3- or 2,3-disubstituted indenopyrazol-4(1H)-ones (4 or 7).The synthesis of the enaminoketones (2 or 5) is accomplished by way of amine addition to the 2-acyl-1,3-indandiones 8a-c or by reduction of the indenoisoxazole 9.The structural assignment of the isomeric indenopyrazoles 4 and 7 is based upon 1H-nmr chemical shifts.