68960-59-8Relevant academic research and scientific papers
Kinetic Resolution by Asymmetric Oxidation of Racemic 3-Azetidinyl P. Tolyl Sulfide with t-Butylhydroperoxide in Presence of a Chiral Titanium Complex
Nemecek, C.,Kagan, H.B.
, p. 2467 - 2476 (2007/10/02)
A chiral reagent based on t-BuOOH and the combination Ti(OiPr)4/(R,R)-DET/H2O=1:2:1 allowed enantioselective oxidation of racemic sulfide β-lactam 2b.By this way recovered 2b could be obtained with ee close to 90percent.The kinetic resolution which was observed was analyzed and discussed. kinetic resolution/β-lactam/racemic sulfide/asymmetric sulfoxidation/hydroperoxide/sulfoxide
