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6898-45-9

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6898-45-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6898-45-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,9 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6898-45:
(6*6)+(5*8)+(4*9)+(3*8)+(2*4)+(1*5)=149
149 % 10 = 9
So 6898-45-9 is a valid CAS Registry Number.

6898-45-9Relevant articles and documents

Synthesis of 1-O-alkyl-2-O-methyl-glycerophospholipids with potential antitumor activity

Alunni-Bistocchi,Orvietani,Ricci,Binaglia,Orlando,Orlando

, p. 499 - 509 (2007/10/02)

Some synthetic alkyl-lysophospholipid analogs have been described as a new class of immunopotentiating and antitumor agents. Among them, 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine has been reported to possess the highest antitumor activity. A new method for the synthesis of this compound and of the ethanolamine- and serine-containing analog is reported. 1-Alkyl-2-methyl-rac-glycerol, prepared from 1,2-isopropylidene-glycerol, is phosphorylated and the intermediate is condensed either with N-t-BOC-protected ethanolamine or with N-t-BOC-protected serine benzhydryl ester. The choline-derivative is obtained by methylation with CH3I of the ethanolamine derivative. The same synthetic sequence has been used also for synthesizing compounds unsaturated at the fatty alkyl chain in position 1 of the glycerol moiety. Preliminary observation are reported on the selective cytolytic action of the compounds on a tumor cell line.

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