69015-82-3Relevant articles and documents
A catalytic asymmetric hetero-Diels-Alder reaction of olefinic azlactones and isatins: Facile access to chiral spirooxindole dihydropyranones
Gao, Tai-Ping,Lin, Jun-Bing,Hu, Xiu-Qin,Xu, Peng-Fei
, p. 8934 - 8936 (2014/08/05)
A catalytic asymmetric hetero-Diels-Alder (HDA) reaction has been achieved through hydrogen-bond directed γ-addition of olefinic azlactones to isatins. This methodology provides an efficient access to spirooxindole dihydropyranones in moderate to good yie
Side chain methyl substitution in the δ-opioid receptor antagonist TIPP has an important effect on the activity profile
Tourwé, Dirk,Mannekens, Els,Diem, Trang Nguyen Thi,Verheyden, Patricia,Jaspers, Hendrika,T?th, Géza,Péter, Antal,Kertész, Istvan,T?r?k, Gabriella,Chung, Nga N.,Schiller, Peter W.
, p. 5167 - 5176 (2007/10/03)
The δ-opioid antagonist H-Tyr-Tic-Phe-Phe-OH (TIPP-OH) or its C- terminal amide analogue was systematically modified topologically by substitution of each amino acid residue by all stereoisomers of the corresponding β-methyl amino acid. The potency and se
On the Synthesis of Geometric Isomers of 2-Methyl (or Phenyl)-4--5(4H)-oxazolones
Cativiela, C.,Diaz de Villegas, M. D.,Melendez, E.
, p. 1655 - 1657 (2007/10/02)
Several Z-2-methyl(or phenyl)-4--5(4H)-oxazolones 3Z, 4Z were prepared.The results obtained were compared by diazomethane insertion and condensation procedure.In order to synthetize E-2-phenyl-4--5-(4H)-oxazolones 4E hy
