69022-35-1

Usage

InChI:InChI=1/C8H8N2/c1-6-7(5-9)3-2-4-8(6)10/h2-4H,10H2,1H3

Upstream product

• 71516-35-3 2-methyl-3-nitrobenzonitrile 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 603-83-8 3-nitro-o-tolylamine 

Downstream Products

• 55289-04-8 3-hydroxy-2-methylbenzonitrile 
• 79237-90-4 2-Methyl-3-(3-nitro-pyridin-2-ylamino)-benzonitrile 
• 16319-04-3 2-(3-Cyano-2-methyl-phenylamino)-benzoic acid 
• 188867-90-5 3-cyano-2-methylphenyl azide 
• 244755-70-2 2-methyl-3-cyano-4-thiocyanatoaniline 
• 1352835-11-0 4-(3-amino-2-methylphenyl)-7-(2-methoxyethoxy)-9H-pyrido[3,4-b]indole-1-carboxamide 
• 1352835-12-1 2-((3-(1-carbamoyl-7-(2-methoxyethoxy)-9H-pyrido[3,4-b]indol-4-yl)-2-methylphenylamino)methyl)-5-chlorobenzoic acid 
• 1352835-10-9 benzyl 3-(1-carbamoyl-7-(2-methoxyethoxy)-9H-pyrido[3,4-b]indol-4-yl)-2-methylphenylcarbamate 
• 1352835-09-6 4-(3-(benzyloxycarbonylamino)-2-methylphenyl)-7-(2-methoxyethoxy)-9H-pyrido[3,4-b]indole-1-carboxylic acid 
• 1352835-08-5 ethyl 4-(3-(benzyloxycarbonylamino)-2-methylphenyl)-7-(2-methoxyethoxy)-9H-pyrido[3,4-b]indole-1-carboxylate 
• 1352835-07-4 benzyl 3-(2-amino-1-(6-(2-methoxyethoxy)-1H-indol-3-yl)ethyl)-2-methylphenylcarbamate 
• 1352835-05-2 benzyl 3-(1-(6-(2-methoxyethoxy)-1H-indol-3-yl)-2-nitroethyl)-2-methylphenylcarbamate 
• 1352835-04-1 (E)-benzyl 2-methyl-3-(2-nitrovinyl)phenylcarbamate 
• 1352835-00-7 benzyl 3-formyl-2-methylphenylcarbamate 

Relevant academic research and scientific papers

ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

CARBOLINE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS

Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, formula (I) are useful as kinase modulators, including Btk modulation.

Increasing the scope of palladium-catalyzed cyanations of aryl chlorides

An improved protocol for the palladium-catalyzed cyanation of electron-rich aryl chlorides with potassium ferrocyanide [K4[Fe(CN)6]] is presented. Compared to previous procedures the substrate scope is significantly broadened.

The scope and limitations of cyanide groups as direction labels for the conformational analysis of matrix-isolated molecules of low symmetry Part 2: 3-Cyanophenyl azide and two conformationally restrained derivatives

3-Cyanophenyl azide and derivatives with ortho methyl groups were photolysed with plane-polarized light in N2 matrices at 12-20 K. The resulting matrices containing the methyl-substituted derivatives had pronounced IR linear dichroism, which wa