690229-61-9Relevant academic research and scientific papers
P2O5/SiO2: A simple and effective catalyst for the synthesis of nsubstituted 1-alkyl and 1-aryl 3-aminoisoquinolines
Mendez, Leticia J.,Canepa, Alicia S.,Rimada, Ruben,Bravo, Rodolfo D.
, p. 240 - 244 (2013/07/26)
A synthesis of N-substituted 1-alkyl and 1-aryl 3-aminoisoquinolines by cyclocondensation of 2-acylphenylacetonitriles with aliphatic and aromatic amines using P2O5/SiO2 as catalysts is described. Selectivity, simplicity o
Aryne insertion into α-cyanocarbonyl compounds: Direct introduction of carbonyl and cyanomethyl moieties into the aromatic skeletons
Yoshida, Hiroto,Watanabe, Masahiko,Ohshita, Joji,Kunai, Atsutaka
, p. 6729 - 6731 (2007/10/03)
Two different carbon functional groups can be introduced simultaneously into 1,2-positions of aromatic skeletons based upon a novel insertion reaction of arynes into a carbonyl-cyanomethyl σ-bond of α-cyanocarbonyl compounds.
A Convenient Synthesis of 2-Acylphenylacetonitriles
Canepa, Alicia S.,Bravo, Rodolfo D.
, p. 579 - 588 (2007/10/03)
The reaction of 2-cyanomethylbenzoyl chloride with Grignard reagents in the presence of cuprous iodide at -5°C easily affords 2-acylphenylacetonitriles with good yield.
