69038-75-1

Usage

General Description

4,6-DIBROMO-1H-BENZIMIDAZOLE is a chemical compound with the molecular formula C7H4Br2N2. It is a derivative of benzimidazole and is characterized by the presence of two bromine atoms at the 4 and 6 positions on the benzene ring. 4,6-DIBROMO-1H-BENZIMIDAZOLE is of interest in the field of medicinal chemistry due to its potential biological activities, including antimicrobial and antitumor properties. It is also used as a building block in the synthesis of various organic compounds. 4,6-DIBROMO-1H-BENZIMIDAZOLE has the potential for further research and development in the pharmaceutical and agrochemical industries.

Upstream product

• 827-23-6 2,4-dibromo-6-nitroaniline 
• 1758-73-2 Aminoiminomethanesulfinic acid 
• 64-18-6 formic acid 
• 1575-38-8 3,5-dibromo-1,2-phenylendiamine 

Relevant academic research and scientific papers

Synthesis of imidazo[4,5-e]benzo[1,2-c;3,4-c′]difuroxanes

A method for the synthesis of imidazo[4,5-e]benzo[1,2-c;3,4-c′]difuroxanes, potential nitric oxide donors, has been developed. The synthesized compounds were characterized by IR and NMR spectroscopy, high resolution mass spectrometry, and elemental analysis.

Convenient two-step one-pot synthesis of benzimidazoles using 2-nitroanilines and thiourea dioxide

A new convenient method for the conversion of 2-nitroanilines into benzimidazoles by two-step one-pot procedure is reported. The procedure involves the reduction of nitro group followed by the intramolecular cyclisation of the corresponding o-phenylenediamines utilising thiourea dioxide and sodium hydroxide at 70 °C in mixed solvents of H2O and EtOH (v/v, 3/1). The yields are good to excellent and the workup is simple.