690631-47-1

Upstream product

• 42726-73-8 methyl t-butyl malonate 
• 690631-42-6 (1R)(2E) dimethyl [1-(methoxycarbonyloxy)-4-(3-methoxyphenyl)-2-butenyl] phosphonate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 690631-40-4 (1R)-dimethyl [1-hydroxy-2-propenyl] phosphonate 
• 690631-43-7 [(E)-(R)-1-Hydroxy-4-(3-methoxy-phenyl)-but-2-enyl]-phosphonic acid dimethyl ester 
• 1039731-28-6 dimethyl [1-(methoxycarbonyloxy)-5-methyl-2-hexenyl]phosphonate 
• 24743-14-4 1-allyl-3-methoxybenzene 

Downstream Products

• 77756-19-5 (R)-4-<(3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 690631-39-1 3-(tert-butoxycarbonyl)-4-[(3-methoxyphenyl)methyl]-dihydro-2(3H)-furanone 

Relevant academic research and scientific papers

Stereospecific Pd(O)-Catalyzed Malonate Additions to Allylic Hydroxy Phosphonate Derivatives: A Formal Synthesis of (-)-Enterolactone

A combination of cross-metathesis and malonate addition was applied to a formal synthesis of the mammalian lignan enterolactone 5. The cross-metathesis of alkene 6 and phosphonate 3a gave the substituted allylic phosphonate 3d. The palladium-catalyzed add