690645-98-8

Basic information

• Product Name: 4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID
• Synonyms: BENZOIC ACID, 4-[[[(3-CHLOROPHENYL)SULFONYL]AMINO]METHYL]-;4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID;4-(((3-Chlorophenyl)sulfonamido)methyl)benzoic acid
• CAS NO: 690645-98-8
• Molecular Formula: C₁₄H₁₂ClNO₄S
• Molecular Weight: 325.77
• Mol File: 690645-98-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 217-219℃
• Appearance: /
• CAS DataBase Reference: 4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID(690645-98-8)
• EPA Substance Registry System: 4-(([(3-CHLOROPHENYL)SULFONYL]AMINO)METHYL)BENZOIC ACID(690645-98-8)

Safety Data

• Hazardous Substances Data: 690645-98-8(Hazardous Substances Data)

Usage

Uses

4-[[[(3-Chlorophenyl)sulfonyl]amino]methyl]benzoic Acid is a selective inhibitor of the 11β-hydroxysteroid dehydrogenase type 1

Upstream product

• 1186212-01-0 methyl 4-[(3-chlorophenylsulfonamido)methyl]benzoate 

Downstream Products

• 727689-14-7 3-chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benzenesulfonamide 
• 690245-46-6 3-chloro-N-[4-(piperidine-1-carbonyl)benzyl]benzenesulfonamide 
• 1186211-92-6 3-chloro-N-[4-(morpholine-4-carbonyl)benzyl]benzenesulfonamide 
• 690245-48-8 3-chloro-N-[4-(4-methylpiperazine-1-carbonyl)benzyl]benzenesulfonamide 
• 1186211-96-0 4-[(3-chlorophenylsulfonamido)methyl]-N-cycloheptylbenzamide 
• 1186211-97-1 4-[(3-chlorophenylsulfonamido)methyl]-N-cycloheptyl-N-methylbenzamide 
• 1186211-98-2 4-[(3-chlorophenylsulfonamido)methyl]-N-cycloheptyl-N-propylbenzamide 
• 1186211-94-8 4-[(3-chlorophenylsulfonamido)methyl]-N-cyclohexylbenzamide 
• 1186211-93-7 4-[(3-chlorophenylsulfonamido)methyl]-N,N-diethylbenzamide 
• 1186211-95-9 4-[(3-chlorophenylsulfonamido)methyl]-N-cyclopentylbenzamide 
• 1186211-99-3 N-butyl-4-[(3-chlorophenylsulfonamido)methyl]-N-cycloheptylbenzamide 
• 1186211-87-9 3-chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-carbonyl]benzyl}benzenesulfonamide 

Relevant articles and documents

4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice

Selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) have considerable potential as treatments for type 2 diabetes. Presented herein are the syntheses, structure-activity relationships, and efficacy evaluation of 4-(phenylsulfonamido