69087-52-1

Upstream product

• 35334-80-6 C₂₅H₂₆O₈S₂ 
• 19132-06-0 (2S,3S)-butane-2,3-diol 
• 100-52-7 benzaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 35572-34-0 (4S,5S)-4,5-dihydroxymethyl-2-phenyldioxolane 
• 38270-72-3 dimethyl 2,3-O-benzylidene-L-tartrate 
• 94730-27-5 (4S,5S)-2-phenyl-4,5-di(methanesulphonyloxymethyl)-1,3-dioxolan 

Downstream Products

• 72300-85-7 erythro-(2S,3R)-3-bromo-2-butyl benzoate 
• 114418-31-4 (2S,3S)-3-Benzyloxy-butan-2-ol 
• 114418-30-3 (2R,3S)-3-(benzyloxy)butan-2-ol 

Relevant academic research and scientific papers

Asymmetric Induction by a Nitrogen14N/15N Isotopomer in Conjunction with Asymmetric Autocatalysis

Chirality arising from isotope substitution, especially with atoms heavier than the hydrogen isotopes, is usually not considered a source of chirality in a chemical reaction. An N2,N2,N3,N3-tetramethyl-2,3-butan

Graphene-catalyzed transacetalization under acid-free conditions

1,2- and 1,3-Diols are readily protected as cyclic acetals and ketals through a graphene-catalyzed transacetalization process. The methodology features an atom economic procedure since quasi-stoichiometric conditions have been developed. Unlike prior systems, the graphene-catalyzed transacetalization is performed under Br?nsted and Lewis acid-free conditions and without solvent. Our method has been applied to several volatile compounds that are unsuitable for complex work-up and extensive purification steps. The very unusual catalytic properties of graphene for transacetalization reactions are ascribed to molecular charge transfer between graphene and substrates.

CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND

The present invention relates to a cyclisation process of forming a multiple ring compound from an isoprenoid compound. The cyclisation process involves reacting the isoprenoid compound with an acetal initiator under conditions sufficient to form the multiple ring compound. The isoprenoid compound is contacted with an initiator an optionally with a catalyst. Cyclisation occurs by reaction of the initiator with the isoprenoid compound. Cyclic aceta compounds wherein the acetal forms part of 6-membered unsaturated ring are also defined.

AN ECONOMICAL LARGE SCALE PREPARATION OF (2S,3S)-4,5-DIMETHYL-2-PHENYL-1,3-DIOXOLAN

An economical 5-step synthesis of (2S,3S)-4,5-dimethyl-2-phenyl-1,3-dioxolan from (2R,3R)-tartaric acid is described.