69116-71-8

Usage

Uses

Used in Organic Synthesis:
Methyl 2-(fluoroformyl)difluoroacetate is utilized as a key intermediate in organic synthesis, contributing to the formation of a variety of complex molecules and materials.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Methyl 2-(fluoroformyl)difluoroacetate is used as a raw material for the production of various pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
Methyl 2-(fluoroformyl)difluoroacetate also finds application in the agrochemical sector, where it serves as a starting material for the synthesis of pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in the Synthesis of Fine Chemicals:
Methyl 2-(fluoroformyl)difluoroacetate is employed in the creation of fine chemicals, which are high-purity chemicals used in various industries, including fragrances, flavors, and specialty chemicals.
Safety Precautions:
Given its potential hazards, Methyl 2-(fluoroformyl)difluoroacetate should be handled with care. It is crucial to work in a well-ventilated area and wear appropriate protective equipment to ensure safety during its use in various applications.

InChI:InChI=1/C4H3F3O3/c1-10-3(9)4(6,7)2(5)8/h1H3

Upstream product

• 755-73-7 methyl 3-methoxy-2,2,3,3-tetrafluoropropionate 
• 268226-88-6 Methyl pentafluoro-3,4-epoxybutanate 

Downstream Products

• 379-95-3 dimethyl 2,2-difluoro-malonate 

Relevant academic research and scientific papers

Perfluoroepoxycarboxylates. Preparation and some properties

Perfluoroepoxycarboxylates were obtained by oxidation with molecular oxygen of esters of unsaturated perfluoroepoxycarboxylic acids CF2=CF(CF2)nCO2CH3 under UV irradiation. The isomeric transformations and thermal stability of the methyl pentafluoro-3,4-epoxybutanate were studied. In the reaction of the above compound with Et3N was obtained methyl tetrafluoro-3-fluoroformylpropanate, and with SbF5 on graphite arised methyl pentafluoroacetate.

Process for the preparation of perfluorinated carboxylic acid fluorides

Perfluorinated carboxylic acid fluorides which also have an ester group in the molecule are prepared by decomposition of perfluorinated fluorosulfato compounds of the formula I STR1 in which R=alkyl, aryl or aralkyl with preferably up to 10 C atoms, in particular CH3 l or C2 H5, m=an integer from 1 to 10, preferably 1 to 8 and in particular 1 to 6, and n=0 or an integer from 1 to 10, preferably 0 to 3 or in particular 0 or 1, in the presence of catalytic amounts of at least one alkali metal fluoride and in the absence of solvents; the compounds have the formula II STR2 in which R, m and n have the same meaning as in formula I. The compounds II are valuable intermediates, in particular for the preparation of perfluorinated vinyl compounds, which can in turn be processed to homopolymers and copolymers which are exceptionally stable to chemicals or heat.

Preparation of fluorocarbonyl compounds

Fluorinated carbonyl compounds are prepared by contacting a fluorinated methyl or ethyl ether containing at least one methoxylated carbon atom-containing group selected from: --CF2 OR3, =CFOR3, STR1 wherein R3 is CH3 or C2 H5, with a catalyst selected from: SbX5, TaX5, NbX5, AsX5, BiX5, TiX4, ZrX4, HfX4, FeX3, mixtures of SbX3 and SbX5, ZM'X'6, and mixtures of ZM'X'6 and M'X5 where X, independently, is F, Cl, Br or I, X' is F or Cl; and Z is H, NO, O2, alkali metal or NY4 where Y, independently, is H or alkyl of 1 to 6 carbon atoms, and M' is Sb or As at a temperature of -20° to 200° C.

Alkyl perfluoro-ω-fluoroformyl esters and monomers therefrom

Alkyl perfluoro-ω-fluoroformyl esters are provided which have the formula STR1 wherein R is alkyl of 1-6 carbon atoms, and N IS 0-6 (PREFERABLY 0). Compounds where n is 0 are prepared by contacting SO3 with a compound of the formula Compounds where n is 1-6 are prepared by contacting a compound where n is 0 with hexafluoropropylene oxide. Also provided are polymerizable monomers having the formula STR2 wherein Y is --COOR, --COOH, --COOM or --CN, where M is an alkali metal, ammonium or quaternary ammonium and p is 1-5, prepared from alkyl perfluoro-ω-fluoroformyl esters of this invention.