691397-24-7Relevant academic research and scientific papers
ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS
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Paragraph 0347, (2018/11/21)
The present invention is drawn to artificial metalloenzymes for use in cyclopropanation reactions, amination and C—H insertion.
Chemoselective, enzymatic C-H bond amination catalyzed by a cytochrome P450 containing an Ir(Me)-PIX cofactor
Dydio, Pawel,Key, Hanna M.,Hayashi, Hiroki,Clark, Douglas S.,Hartwig, John F.
supporting information, p. 1750 - 1753 (2017/02/15)
Cytochrome P450 enzymes have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these reactions have been limited by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrate t
Copper-catalyzed intramolecular C-H amination
Barman, Dipti N.,Nicholas, Kenneth M.
supporting information; experimental part, p. 908 - 911 (2011/04/26)
The amino-functionalization of tertiary, secondary and benzylic C-H bonds of tethered carbamates and sulfamates by iodosobenzene is catalyzed by Cu I-diimine complexes in moderate to good yield. Employing homochiral imine-Cucatalysts affords oxazolidinones and oxathiazinanes with modest enantioselectivity.
Asymmetric transfer of nitrenes catalyzed by chiral dirhodium(II) using aromatic sulfamate esters
Fruit, Corinne,Mueller, Paul
, p. 1019 - 1026 (2007/10/03)
Enantioselective intra- and intermolecular insertions of aromatic sulfamate esters into activated C-H bonds have been achieved via in situ generated phenyliodinanes in the presence of PhI(OAc)2, MgO, and chiral Rh(II) catalysts. The optimal results were obtained with [Rh 2{(S)-nttl}4] and [Rh2{(R)-ntv}4] as catalysts with up to 52% ee. In contrast, phenylsulfamates with allylic ortho-substituents reacted via intramolecular aziridination rather than insertion. The intermolecular amidation of indane proceeded with up to 97% yield when the reaction was carried out with the sulfamate in excess.
