691406-44-7

Basic information

• Product Name: 5-(2-phenyl-ethyl)-4-(2-hydroxy-ethyl)-3-isoxazolecarboxylic acid ethyl ester
• Synonyms: 5-(2-phenyl-ethyl)-4-(2-hydroxy-ethyl)-3-isoxazolecarboxylic acid ethyl ester
• CAS NO: 691406-44-7
• Molecular Weight: 289.331
• Mol File: 691406-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2-phenyl-ethyl)-4-(2-hydroxy-ethyl)-3-isoxazolecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-phenyl-ethyl)-4-(2-hydroxy-ethyl)-3-isoxazolecarboxylic acid ethyl ester(691406-44-7)
• EPA Substance Registry System: 5-(2-phenyl-ethyl)-4-(2-hydroxy-ethyl)-3-isoxazolecarboxylic acid ethyl ester(691406-44-7)

Safety Data

• Hazardous Substances Data: 691406-44-7(Hazardous Substances Data)

Upstream product

• 216962-31-1 5-(2-phenyl-ethyl)-4-(methoxycarbonyl)methyl-3-isoxazolecarboxylic acid ethyl ester 
• 216962-18-4 5-(2-phenyl-ethyl)-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)-3-isoxazolecarboxylic acid ethyl ester 
• 216962-29-7 5-(2-phenyl-ethyl)-4-(1-keto-ethyl)-3-isoxazolecarboxylic acid ethyl ester 
• 216962-12-8 3-isoxazolecarboxylic acid 5-methyl-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)-ethyl ester 

Downstream Products

• 691406-51-6 5-(2-phenyl-ethyl)-4-(2-oxo-ethyl)-3-isoxazolecarboxylic acid ethyl ester 
• 691406-81-2 (S)-5-(2-phenyl-ethyl)-4-(2-amino-2-methoxycarbonyl-ethyl)-3-isoxazolecarboxylic acid ethyl ester 
• 691406-73-2 (S)-5-(2-phenyl-ethyl)-4-(N-[allyl]-2-amino-2-methoxycarbonyl-ethyl)-3-izoxazolecarboxylic acid ethyl ester 

Relevant articles and documents

Catalytic asymmetric synthesis of glutamate analogues

Utilizing our lateral metalation coupled with Jacobsen's catalytic asymmetric amino nitrile synthesis, we have demonstrated the ability to synthesize isoxazole-containing amino acid glutamate analogues in high yield and high enantiomeric excesses. Chiral