691407-62-2

Upstream product

• 691407-44-0 C₂₀H₂₃NO₅ 
• 691891-09-5 (2S,3R,4S,5S)-2,3-dihydroxy-cephalotaxan-8-one 
• 691407-39-3 (6R)-7-[2-(3,4-methylenedioxyphenyl)ethyl]-1,4-dioxa-7-azadispiro[4.0.4.3]tridecan-8-one 
• 691891-08-4 (4S,5S)-2,3-didehydro-cephalotaxan-8-one 
• 691407-41-7 (5S)-1-[2-(3,4-methylenedioxyphenyl)ethyl]-1-azaspiro[4.4]non-7-ene-2,6-dione 
• 691407-42-8 (S)-1-(2-Benzo[1,3]dioxol-5-yl-ethyl)-6-hydroxy-1-aza-spiro[4.4]non-7-en-2-one 
• 502622-15-3 (6R)-7-[(1S)-1-(1-naphthyl)ethyl]-1,4-dioxa-7-azadispiro[4.0.4.3]tridecan-8-one 
• 502622-13-1 (5R)-1-[(1S)-1-(1-naphthyl)ethyl]-1-azaspiro[4.4]nonane-2,6-dione 
• 502622-16-4 (6R)-1,4-dioxa-7-azadispiro[4.0.4.3]tridecan-8-one 
• 187106-18-9 (5R)-1-[2-(3,4-methylenedioxyphenyl)ethyl]-1-azaspiro[4.4]nonane-2,6-dione 
• 691407-56-4 C₂₇H₂₉NO₅ 
• 691407-40-6 (5R)-1-[2-(3,4-methylenedioxyphenyl)ethyl]-6-trimethylsilyloxy-1-azaspiro[4.4]non-6-en-2-one 

Downstream Products

• 691407-66-6 (4S,5S,7S)-1,2-didehydro-2-methoxy-7-benzyl-cephalotaxane-3,8-dione 
• 691407-64-4 (5S,7S)-3,4-didehydro-3-hydroxy-7-benzyl-cephalotaxane-2,8-dione 

Relevant academic research and scientific papers

Stereoselective Synthesis of (-)-Cephalotaxine and C-7 Alkylated Analogues

A total asymmetric synthesis of (-)-cephalotaxine is reported. The chemistry of α,β-unsaturated γ-lactams was used to access the 1-azaspiro[4.4]nonane skeleton in enantiomerically pure form via a stereocontrolled semipinacolic rearrangement of an α-hydrox