691410-72-7

Upstream product

• 691410-73-8 (2S,3R)-3-Acetylamino-2-hydroxy-3-(4-methoxy-phenyl)-propionic acid methyl ester 
• 691410-80-7 (2S,3R)-3-Acetylamino-2-methanesulfonyloxy-3-(4-methoxy-phenyl)-propionic acid methyl ester 
• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 

Downstream Products

• 220736-25-4 (4R,5R)-cytoxazone 
• 691410-75-0 (4R,5R)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylic acid 
• 691410-76-1 methyl (4R,5R)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylate 

Relevant academic research and scientific papers

Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone

Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31% overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the confi