69142-66-1Relevant academic research and scientific papers
Regioselective synthesis of dispirocycloalkanooxindolopyrrolidines and dispirocyclalkanoindanopyrrolidines
Poornachandran, Mahalingam,Jayagobi, Mathesan,Raghunathan, Raghavachary
, p. 551 - 563 (2010)
Synthesis of a series of novel dispirocycloalkanone-oxindolopyrrolidines and dispirocycloalkanone-indanopyrrolidines is described. The nonstabilized azomethine ylides generated from a secondary amino acid, sarcosine, and carbonyl components (isatin and ninhydrin) have been effectively trapped by the dipolarophiles, arylidene cycloalkanones, to afford dispiropyrrolidines. The one-pot azomethine ylide cycloaddition reactions were highly regioselective. Copyright Taylor & Francis Group, LLC.
Regioselective synthesis of rac-(1R,4R,6R,6aR)-6′-phenyl-7′, 8′-dihydro-1″H,2′H,6′H-dispiro[cycloalkane-1, 5′-pyrrolo[1,2-c][1,3]thiazole-4′,3″-indole]-2, 2″-diones through 3 + 2 cycloaddition reaction
Poornachandran, Mahalingam,Jayagobi, Mathesan,Raghunathan, Raghavachary
scheme or table, p. 240 - 243 (2009/12/07)
Synthesis of a series of novel rac-(1R,4R,6R,6aR)-6′-phenyl-7′, 8′-dihydro-1″H,2′H,6′H-dispiro[cycloalkane-1, 5′-pyrrolo[1,2-c][1,3]thiazole-4′,3″-indole]-2, 2″-diones by cycloaddition reaction is described. The nonstabilised azomethine ylide generated by the reaction of isatin and thiazolidine-2- carboxylic acid has been regioselectively trapped by various substituted benzylidene cycloalkanones.
A new lewis acid system palladium/TMSCl for Catalytic aldol condensation of aldehydes with ketones
Zhu, Yulin,Pan, Yuanjiang
, p. 668 - 669 (2007/10/03)
Palladium on charcoal effectively catalyzed the aldol condensation reactions of different ketones with aldehydes in the presence of trimethylsilyl chloride (TMSCl). The following reactions were investigated: (1) aromatic aldehydes with cycloalkanones, (2) aromatic aldehydes with aromatic ketones, (3) cycloalkanones with aliphatic aldehydes, and (4) the self-condensation reactions of aliphatic aldehydes and cycloalkanones.
