69169-71-7

Usage

Uses

Used in Pharmaceutical Research:
8-METHOXY-4-METHYLBENZO[G]COUMARIN is used as a potential anti-cancer and anti-inflammatory agent for its potential therapeutic effects in treating various medical conditions.
Used in Analytical Chemistry:
8-METHOXY-4-METHYLBENZO[G]COUMARIN is used as a fluorescent probe for its potential applications in analytical chemistry.
Used in Drug Development:
8-METHOXY-4-METHYLBENZO[G]COUMARIN is used in the development of new drugs due to its potent antioxidant activity and potential therapeutic effects.

InChI:InChI=1/C15H12O3/c1-9-5-15(16)18-14-8-11-6-12(17-2)4-3-10(11)7-13(9)14/h3-8H,1-2H3

Upstream product

• 69169-70-6 8-hydroxy-4-methyl-2H-naphtho<2,3-b>-pyran-2-one 
• 74-88-4 methyl iodide 
• 5060-82-2 7-methoxy-2-naphthol 
• 141-97-9 ethyl acetoacetate 

Relevant academic research and scientific papers

Environment-sensitive fluorophore emitting in protic environments

(Diagram presented) The unusual fluorescence properties of 8-methoxy-4-methyl-2H-benzo[g]chromen-2-one (1) are described. The fluorophore 1 is almost nonfluorescent in aprotic solvent (e.g., fluorescence quantum yield Φf 450 nm) in protic solvent (e.g., Φf = 0.21 in methanol). The fluorophore 1 also shows good applicability in developing a new fluorogenic (fluorescent "off-on") sensor.

Comparative study of polyaromatic and polyheteroaromatic fluorescent photocleavable protecting groups

Fluorescent conjugates of N-benzyloxycarbonyl protected γ-aminobutyric acid were prepared by coupling to its C-terminus several polyheteroaromatic, based on the oxobenzopyran skeleton (trivially known as coumarin) and polyaromatic labels, such as naphthalene and pyrene. Photophysical properties were evaluated, as well as their behaviour towards photocleavage by irradiation in MeOH/HEPES buffer solution (80:20), in a photochemical reactor at different wavelengths (254, 300, 350 and 419 nm), followed by HPLC/UV monitoring.