5060-82-2

Basic information

• Product Name: 7-METHOXY-2-NAPHTHOL
• Synonyms: 7-METHOXY-2-NAPHTHOL;7-methoxynaphthalen-2-ol;2-Hydroxy-7-methoxynaphthalene;3-Methoxy-6-naphthol;7-Methoxy-2-naphthalenol;7-Methoxy-beta-naphthol;7-Methoxy-2-naphthol, 97%, 97%;7-Methoxy-2-naphthol 98%
• CAS NO: 5060-82-2
• Molecular Formula: C₁₁H₁₀O₂
• Molecular Weight: 174.2
• Product Categories: Organic Building Blocks;Oxygen Compounds;Phenols;Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 5060-82-2.mol

Chemical Properties

• Melting Point: 116-119 °C(lit.)
• Boiling Point: 336.7 °C at 760 mmHg
• Flash Point: 211.9 °C
• Appearance: White to brown/Crystalline Powder or Chunks
• Density: 1.193
• Vapor Pressure: 5.65E-05mmHg at 25°C
• Refractive Index: 1.64
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.45±0.40(Predicted)
• BRN: 2207279
• CAS DataBase Reference: 7-METHOXY-2-NAPHTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-2-NAPHTHOL(5060-82-2)
• EPA Substance Registry System: 7-METHOXY-2-NAPHTHOL(5060-82-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 8-9-23
• Hazardous Substances Data: 5060-82-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
7-Methoxy-2-naphthol is used as a chemical intermediate for the synthesis of new 1H-benzo[f]chromene derivatives, which are important in various chemical applications.
Used in Analytical Chemistry:
In the synthesis of 7-methoxy-2-naphthyl (MN)-derived xylosides, 7-Methoxy-2-naphthol serves as a marker for Nuclear Magnetic Resonance (NMR) characterization and Ultraviolet (UV) detection, making it a valuable tool in analytical chemistry for identifying and quantifying specific compounds.

InChI:InChI=1/C11H10O2/c1-13-11-5-3-8-2-4-10(12)6-9(8)7-11/h2-7,12H,1H3

Upstream product

• 67-56-1 methanol 
• 582-17-2 2,7-Dihydroxynaphthalene 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 47644-69-9 dimethyl 2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylate 
• 79044-29-4 7,7'-dimethoxy-1,1'-binaphthalene-2,2'-diol 
• 128702-25-0 Methyl 2,2'-dihydroxy-7'-methoxy-1,1'-binaphthalene-3-carboxylate 
• 75965-66-1 2-hydroxy-7-methoxynaphthalene-1-carbaldehyde 
• 1012319-89-9 C₂₀H₁₆O₃ 
• 582-17-2 2,7-Dihydroxynaphthalene 
• 1260082-94-7 C₂₅H₁₉ClN₂O₂S 
• 1449701-22-7 (E)-1-benzylidene-N-butyl-5-methoxy-1H-indene-3-carboxamide 
• 1449701-27-2 (E)-N-benzyl-1-benzylidene-5-methoxy-1H-indene-3-carboxamide 
• 1449701-59-0 (E)-1-benzylidene-5-methoxy-N-phenyl-1H-indene-3-carboxamide 
• 1449701-71-6 (E)-phenethyl 1-benzylidene-5-methoxy-1H-indene-3-carboxylate 
• 1449701-80-7 (E)-4-acetylphenyl 1-(furan-2-ylmethylene)-5-methoxy-1H-indene-3-carboxylate 
• 1364525-17-6 7-benzylnaphthalen-2-ol 
• 26593-50-0 7-methylnaphthalen-2-ol 

Relevant articles and documents

Regioselective Monomethylation of Unsymmetrical Naphthalenediols with Methanolic HCl

Treatment of naphthalene-1,3-diol and naphthalene-1,7-diol with methanol containing dry hydrogen chloride at room temperature gives exclusively 3-methoxy-1-naphthol and 7-methoxy-1-naphthol, respectively.Of the other two unsymmetrical naphthalenediols, the 1,2-isomer was unreactive and the 1,6-isomer gave a mixture of regioisomers under the same conditions.Two symmetrical diols (the 1,5- and 2,7-isomers) examined by the same procedure gave the monomethyl ethers in 60-70percent yields.

HALOGENATION REGIOSELECTIVE EN SERIE AROMATIQUE-II CHLORATION DES NAPHTOLS ET LEURS ETHERS A L'AIDE DE REACTIFS METTANT EN JEU DES INTERACTIONS DU TYPE DONNEUR-ACCEPTEUR

The regispecific chlorination of naphtols by hexachlorocyclohexadienones as selective chlorinating reagents is described.The selectivity attained is better than that which we have obtained with phenol derivatives and confirms the importance of the donor-acceptor interaction between the reagent and the naphthol during the chlorination.