69184-79-8

Basic information

• Product Name: 3-phenyl-2,4,5,6,7,7a-hexahydrobenzo[b]furan-2-one
• Synonyms: 3-phenyl-2,4,5,6,7,7a-hexahydrobenzo[b]furan-2-one
• CAS NO: 69184-79-8
• Molecular Weight: 214.264
• Mol File: 69184-79-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-phenyl-2,4,5,6,7,7a-hexahydrobenzo[b]furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-2,4,5,6,7,7a-hexahydrobenzo[b]furan-2-one(69184-79-8)
• EPA Substance Registry System: 3-phenyl-2,4,5,6,7,7a-hexahydrobenzo[b]furan-2-one(69184-79-8)

Safety Data

• Hazardous Substances Data: 69184-79-8(Hazardous Substances Data)

Upstream product

• 931-17-9 1,2-Cyclohexanediol 
• 83-13-6 diethyl 2-phenylmalonate 
• 108-94-1 cyclohexanone 
• 31491-21-1 2-phenyl-1,1-bis(trimethylsilyloxy)ethene 
• 1728-17-2 α-bromocyclohexanone dimethyl ketal 
• 1056477-06-5 2-bromocyclohexanone 
• 103-82-2 phenylacetic acid 
• 822-87-7 2-Chlorocyclohexanone 

Relevant articles and documents

THE MUKAIYAMA REACTION OF KETENE BIS(TRIMETHYLSILYL)ACETALS WITH α-HALO ACETALS - A CONVENIENT BUTENOLIDE SYNTHESIS

Ketene bis(trimethylsilyl) acetals were reacted with α-halo acetals giving β-alkoxy-γ-halo acids which were converted to butenolides by reaction with equivalents of base.This constitutes a novel and short butenolide synthesis.

Diastereoselective cyclopropanation of ketone enols with Fischer carbene complexes

Treatment of aryl/heteroaryl methoxycarbene complexes of chromium with β-substituted ketone lithium enolates between -78 °C and room temperature resulted in the diastereoselective synthesis of 1,2,2,3-tetrasubstituted cyclopropanols. An exception has been observed in the reaction with cyclohexanone lithium enolate that yielded a bicyclic 2-buten-4-olide. 1,2-Dimethoxycyclopropanes and 1-methoxy-2-trimethylsilyloxycyclopropanes were isolated by quenching the reactions with MeOTf or Me3SiCl, respectively. This novel cyclopropanation process involves formation of lithium (3-oxoalkyl)pentacarbonylchromate intermediates which on warming undergo intramolecular addition to the carbonyl group. This cyclization is equivalent to the cyclopropanation in smooth conditions of electron-rich alkenes with Fischer carbene complexes. Copyright