691856-35-6

Usage

Uses

Used in Pharmaceutical Development:
5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)benzofuran-3-carboxamide is used as a potential candidate for the development of pharmaceutical drugs for various medical purposes. Its unique structural features may contribute to its pharmacological or biological activities, making it a promising compound for further research and testing.
However, it is important to note that the specific applications and industries for 5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-(methylsulfonamido)benzofuran-3-carboxamide have not been provided in the materials. Further research and testing are needed to fully understand its properties and potential applications in various fields.

Upstream product

• 691857-54-2 5-cyclopropyl-2-(4-fluorophenyl)-6-[(methylsulfonyl)amino]-1-benzofuran-3-carboxylic acid 
• 74-89-5 methylamine 
• 63131-29-3 methyl 4-fluorobenzoyl acetate 
• 691857-51-9 ethyl 2-(4-fluorophenyl)-6-nitro-5-(trifluoromethylsulfonyloxy)benzofuran-3-carboxylate 
• 691856-86-7 ethyl 2-(4-fluorophenyl)-5-hydroxybenzofuran-3-carboxylate 
• 1999-00-4 ethyl 3-(4'-fluorophenyl)-3-oxopropionate 
• 691857-53-1 ethyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)benzofuran-3-carboxylate 
• 691857-52-0 ethyl 5-cyclopropyl-2-(4-fluorophenyl)-6-nitrobenzofuran-3-carboxylate 
• 691857-46-2 ethyl 2-(4-fluorophenyl)-5-hydroxy-6-nitrobenzofuran-3-carboxylate 
• 691857-07-5 ethyl 2-(4-fluorophenyl)-5-isopropoxy-6-nitrobenzofuran-3-carboxylate 
• 1331942-88-1 methyl 2-(4-fluorophenyl)-5-[(1-methylethyl)oxy]-6-nitro-1-benzofuran-3-carboxylate 
• 1331942-87-0 methyl 2-(4-fluorophenyl)-5-[(1-methylethyl)oxy]-1-benzofuran-3-carboxylate 
• 1331942-99-4 methyl 6-[bis(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate 
• 1331942-98-3 methyl 6-amino-5-cyclopropyl-2-(4-fluorophenyl)-1-benzofuran-3-carboxylate 

Downstream Products

• 691857-56-4 6-[(2-benzyloxy-ethyl)-methanesulfonyl-amino]-5-cyclopropyl-2-(4-fluoro-phenyl)-benzofuran-3-carboxylic acid methylamide 
• 1193346-12-1 5-cyclopropyl-6-(ethylsulfonyl-methanesulfonylamino)-2-(4-fluorophenyl)-benzofuran-3-carboxylic acid methylamide 
• 1193346-04-1 5-cyclopropyl-6-(ethenesulfonyl-methanesulfonyl-amino)-2-(4-fluorophenyl)-benzofuran-3-carboxylic acid methylamide 
• 1378432-57-5 6-[(3-[4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-{[(methyloxy)methyl]oxy}propyl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1378432-71-3 6-[(3-[5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-{[(methyloxy)methyl]oxy}propyl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1378432-83-7 6-[(3-[2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-{[(methyloxy)methyl]oxy}propyl)(methylsulfonyl)amino]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1378428-99-9 6-(N-(4-(benzyloxy)-2-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)butyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1378427-34-9 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-((2-hydroxy-1,2-oxaborinan-4-yl)methyl)methylsulfonamido)-N-methylbenzofuran-3-carboxamide 
• 1378429-07-2 6-(N-(4-(benzyloxy)-3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)butyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1378427-36-1 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-(2-(2-hydroxy-1,2-oxaborolan-4-yl)ethyl)methylsulfonamido)-N-methylbenzofuran-3-carboxamide 
• 1378429-17-4 6-(N-(2-(benzyloxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1378427-37-2 5-cyclopropyl-2-(4-fluorophenyl)-6-[[(2-hydroxy-1,2-oxaborinan-5-yl)methyl](methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 
• 1378429-23-2 6-(N-(3-(tert-butyldimethylsilyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1378427-38-3 5-cyclopropyl-2-(4-fluorophenyl)-6-[[2-(2-hydroxy-1,2-oxaborolan-5-yl)ethyl](methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide 

Relevant academic research and scientific papers

INHIBITORS OF HEPATITIS C VIRUS POLYMERASE

The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.

THERAPEUTIC METHODS

The present invention features a method for the treatment of Hepatitis C in a human in need thereof comprising administering a compound of Formulas (II) or (IIB) described herein or a pharmaceutically acceptable salt thereof in combination with one or more alternative Hepatitis C therapeutic agents

BENZOFURAN COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS

The present invention features compounds of formula (I) and salts thereof, pharmaceutical compositions comprising said compounds, and uses of such compounds in treating or preventing viral infections, such as HCV infections, and diseases associated with such infections.

6-SUBSTITUTED BENZOFURAN COMPOUNDS TO TREAT INFECTION WITH HEPATITIS C VIRUS

Compounds of following formula (I); wherein R1, R2, R3, R4, R5, and R6 are as defined herein, including all crystalline forms and pharmaceutically acceptable salts thereof, which are useful in pharmaceutical formulations for the treatment or prevention of

COMBINATION THERAPY METHOD FOR TREATING HEPATITIS C VIRUS INFECTION AND PHARMACEUTICAL COMPOSITIONS FOR USE THEREIN

Combination therapy methods for the treatment of hepatitis C virus infection and associated diseases, by the co-administration of 5-cyclopropyl-2- (4-fluoro-phenyl-6-[(2-hydroxy-ethyl)-methanesulfonyl-amino]-benzofuran- 3-carboxylic acid methylamide or a pharmaceutically acceptable salt thereof with natural, recombinant or modified interferon, that effectively inhibit viral replication.