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6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one, also known as 2-Amino-6-methyldihydro-1H-isoindol-1-one, is an organic chemical compound characterized by the molecular formula C9H10N2O. It presents as a white crystalline powder and is recognized for its role as an intermediate in the synthesis of pharmaceuticals. 6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one is also noted for its potential biological and pharmacological activities, which position it as a significant building block in the development of novel drugs. Furthermore, it has garnered interest for its possible applications in the treatment of neurological disorders and as an inhibitor of specific enzymes, making it a valuable asset in medicinal chemistry and pharmaceutical research.

69189-26-0

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69189-26-0 Usage

Uses

Used in Pharmaceutical Synthesis:
6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one is utilized as a key intermediate in the production of various pharmaceuticals. Its chemical structure allows for the creation of a wide range of drug molecules, contributing to the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one serves as an important building block for the design and synthesis of new drug candidates. Its unique properties facilitate the exploration of novel chemical space and the advancement of drug discovery.
Used in Neurological Disorder Treatment:
6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one has been studied for its potential therapeutic effects in the treatment of neurological disorders. Its pharmacological profile suggests that it may offer benefits in managing such conditions, although further research is necessary to fully understand its mechanisms of action and therapeutic potential.
Used as an Enzyme Inhibitor:
6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one has also been investigated for its potential as an inhibitor of specific enzymes. Its ability to modulate enzymatic activity could have implications for the treatment of various diseases and conditions where enzyme dysregulation plays a role.
Used in Drug Development:
6-Amino-2,3-dihydro-2-methyl-1H-Isoindol-1-one is employed in the development of new drugs due to its potential biological activities. Its incorporation into drug molecules may lead to the discovery of innovative therapeutics with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 69189-26-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,8 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 69189-26:
(7*6)+(6*9)+(5*1)+(4*8)+(3*9)+(2*2)+(1*6)=170
170 % 10 = 0
So 69189-26-0 is a valid CAS Registry Number.

69189-26-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-2-methyl-3H-isoindol-1-one

1.2 Other means of identification

Product number -
Other names 6-azanyl-2-methyl-3H-isoindol-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:69189-26-0 SDS

69189-26-0Downstream Products

69189-26-0Relevant academic research and scientific papers

OGA INHIBITOR COMPOUNDS

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Paragraph 40, (2020/01/11)

The present invention relates to O-GIcNAc hydrolase (OGA) inhibitors of formula (I). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which inhibition of OGA is beneficial, such as tauopathies in particular Alzheimer's disease or progressive supranuclear palsy; and neurodegenerative diseases accompanied by a tau pathology, in particular amyotrophic lateral sclerosis or frontotemporal lobe dementia caused by C90RF72 mutations.

HETEROARYL COMPOUNDS AND USES THEREOF

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Paragraph 00892-00893, (2016/06/28)

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. It has now been found that compounds of this invention, and pharmaceutically acceptable compositions thereof, are effective as inhibitors of one or more protein kinases. Such compounds have general formula I or a pharmaceutically acceptable salt thereof, wherein Ring A, Ring B, W, Ry, R3 and R4 are as defined herein.

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