69190-56-3

Basic information

• Product Name: 2-BROMO-3-CHLOROTOLUENE
• Synonyms: 2-BROMO-3-CHLOROTOLUENE;2-chloro-2-chlorotoluene
• CAS NO: 69190-56-3
• Molecular Formula: C₇H₆BrCl
• Molecular Weight: 205.48
• Product Categories: Halogen toluene;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Chlorine Compounds
• Mol File: 69190-56-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 70/1mm
• Flash Point: 104.5±11.9℃
• Appearance: /
• Density: 1.57
• Vapor Pressure: 0.107mmHg at 25°C
• Refractive Index: 1.566
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BROMO-3-CHLOROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-CHLOROTOLUENE(69190-56-3)
• EPA Substance Registry System: 2-BROMO-3-CHLOROTOLUENE(69190-56-3)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-50
• Safety Statements: 61
• Hazardous Substances Data: 69190-56-3(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-chlorotoluene is a chemical compound with the molecular formula C7H7BrCl. It is a colorless to pale yellow liquid that is sparingly soluble in water. 2-BROMO-3-CHLOROTOLUENE is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a chemical intermediate in the production of dyes, pigments, and other organic compounds. 2-Bromo-3-chlorotoluene is a halogenated aromatic compound and should be handled with care due to its potential hazards and toxicity. It is important to use proper safety precautions when working with this compound to avoid potential health and environmental risks.

InChI:InChI=1/C7H6BrCl/c1-5-3-2-4-6(9)7(5)8/h2-4H,1H3

Upstream product

• 87-63-8 2-chloro-6-methylaniline 
• 570-24-1 2-Methyl-6-nitroaniline 

Downstream Products

• 56961-26-3 2-bromo-3-chlorobenzoic acid 
• 134271-35-5 bis(2-chloro-6-methylphenyl)methanol 
• 87-63-8 2-chloro-6-methylaniline 
• 1021089-12-2 2-bromo-3-chlorophenylacetic acid methyl ester 
• 220453-60-1 2-bromo-3-chlorobenzyl bromide 
• 21327-86-6 2-chloro-6-methylbenzoic acid 
• 89894-44-0 2-chloro-6-methylbenzoyl chloride 
• 116529-64-7 2-bromo-3-chlorobenzoyl chloride 

Relevant articles and documents

Theramutein modulators

This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.

Synthesis of 9,10-dihydrosilaanthracenes with substituents ortho to the silicon and methylene bridges

The generation of 9,10-dihydrosilaanthracenes with substituents on benzo ring carbons, specifically in the 4,5-positions adjacent to the methylene bridge, has been developed.Attempts to prepare the 1,8-isomer where the substituents are adjacent to the silicon bridge are also described.The diarylmethane precursors to the substituted 9,10-dihydrosilaanthracenes required the synthesis of 2,3-dihalotoluenes as well as isomeric 2,6-disubstituted benzaldehydes which were then condensed to diarylmethanols through the Grignard reagents.Ring closure to the 4,5-dimethyl-9,9-dialkyl-9,10-dihydro-9-silaanthracene, I, required the use of Rieke magnesium.The structure of I (alkyl = iPr) was determined and demonstrates that the introduction of substituents adjacent to the methylene bridge causes the dihydrosilaanthracene framework to become nearly planar with a dihedral (or butterfly) angle of 170 deg C.

7 AND 8-Halo substituted 1,2,3,4-tetrahydroisoquinoline compounds

1,2,3,4-Tetrahydroisoquinoline compounds having 7 and 8 halo substituents are inhibitors of phenylethanolamine N-methyltransferase.