69198-17-0Relevant academic research and scientific papers
Synthesis, antibacterial and antifungal activity of 4-substituted-5-aryl-1, 2,4-triazoles
Colanceska-Ragenovic, Katica,Dimova, Vesna,Kakurinov, Vlado,Molnar, Dora Gabor,Buzarovska, Aleksandra
, p. 815 - 824 (2001)
A few 4-allyl/amino-5-aryl-1,2,4-triazoles were synthesized and tested for antibacterial and antifungal effects against Escherichia coli, Bacillus subtilis, Salmonella enteritidis, Staphylococcus aureus, Aspergillus niger and Candida albicans. 4-Allyl-5-aryl-1,2,4-triazoles were obtained by the oxidative cyclization of the appropriate 1-substituted-4-allylthiosemicarbazides and 4-amino-5-aryl-1,2,4-triazoles were obtained by cyclization of the potassium salts of appropriately substituted dithiocarbazinic acids with hydrazine hydrate. The new synthesized compounds were characterized using IR, 1H- NMR, 13C-NMR and UV spectral data together with elemental analysis.
