69214-22-8

Basic information

• Product Name: Imidazo[1,2-a]pyridin-8-ol (9CI)
• Synonyms: Imidazo[1,2-a]pyridin-8-ol (9CI);Imidazo[1,2-a]pyridin-8-ol;8-hydroxy-imidazopyridine;8-Hydroxyimidazo[1,2-a]pyridine 95+%;8-imidazo[1,2-a]pyridinol
• CAS NO: 69214-22-8
• Molecular Formula: C7H6N2O
• Molecular Weight: 134.13534
• Product Categories: AMINETERTIARY
• Mol File: 69214-22-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 154-157°
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Imidazo[1,2-a]pyridin-8-ol (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridin-8-ol (9CI)(69214-22-8)
• EPA Substance Registry System: Imidazo[1,2-a]pyridin-8-ol (9CI)(69214-22-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 69214-22-8(Hazardous Substances Data)

Usage

General Description

Imidazo[1,2-a]pyridin-8-ol (9CI) is a chemical compound with the molecular formula C8H7N2O. It is a heterocyclic compound that contains both nitrogen and oxygen atoms in its structure. Imidazo[1,2-a]pyridin-8-ol (9CI) is used in various pharmaceutical and research applications, including as a building block for the synthesis of other compounds, as a ligand in coordination chemistry, and as a potential drug candidate for the treatment of various diseases. Its precise properties and potential uses are still being studied and evaluated by researchers.

Upstream product

• 107-20-0 2-chloroethanal 
• 16867-03-1 2-amino-3-hydroxypyridine 
• 24016-03-3 2-amino-3-benzyloxypyridine 
• 96428-16-9 8-(phenylmethoxy)imidazo[1,2-a]pyridine 
• 100592-11-8 hydrogen chloride salt of 8-hydroxy-imidazo<1,2-a>pyridine 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING

Provided herein are compounds having activity against TTR related conditions, and pharmaceutically accepted salts and solvates thereof. Also provided are methods of using the compounds for inhibiting and preventing TTR aggregation and/or amyloid formation in the peripheral nerves, kidney, cardiac tissue, eye and CNS, and of treating a subject with peripheral TTR amyloidosis.

Etude de l'hydroxy-8 imidazopyridine. Partie 1 : equilibre tautomerique en solution aqueuse.

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SYNTHESIS OF NEW HETEROCYCLIC PHENOLS: 8-HYDROXY-IMIDAZOPYRIDINE

Preparation of the unknown title compound has been achieved by condensation of 2-amino-3-hydroxy-pyridine with chloroacetaldehyde.Activation by the free phenolic hydroxyl allows preferential nitration of the pyridine ring, in marked contrast to the behavior of the related ethers which suffer electrophilic substitution on the imidazole moiety, as usual in the series.