96428-16-9

Usage

Uses

Used in Pharmaceutical Development:
8-BENZYLOXY-IMIDAZO[1,2-A]PYRIDINE is used as a chemical intermediate for the synthesis of various pharmaceutical drugs. Its unique structure and potential biological activity make it a promising candidate for the development of new medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 8-BENZYLOXY-IMIDAZO[1,2-A]PYRIDINE is used as a research compound to explore its potential pharmacological properties. Scientists and researchers employ 8-BENZYLOXY-IMIDAZO[1,2-A]PYRIDINE to investigate its interactions with biological targets and its efficacy in treating specific diseases.
Used in Drug Discovery:
8-BENZYLOXY-IMIDAZO[1,2-A]PYRIDINE is utilized as a lead compound in drug discovery processes. Its structural features and potential biological activity are assessed to identify possible therapeutic applications and to guide the design of more effective and targeted drugs.

InChI:InChI=1/C14H12N2O/c1-2-5-12(6-3-1)11-17-13-7-4-9-16-10-8-15-14(13)16/h1-10H,11H2

Upstream product

• 107-20-0 2-chloroethanal 
• 24016-03-3 2-amino-3-benzyloxypyridine 
• 16867-03-1 2-amino-3-hydroxypyridine 
• 100-44-7 benzyl chloride 
• 17157-48-1 bromoacetaldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 109388-61-6 (8-Benzyloxy-imidazo[1,2-a]pyridin-3-ylmethyl)-dimethyl-amine; hydrochloride 
• 110241-62-8 3-nitroso-8-(phenylmethoxy)imidazo<1,2-a>pyridine 
• 156817-68-4 hydroxy-8 tetrahydro-5,6,7,8 imidazo<1,2-a>pyridine 
• 109388-59-2 bromo-3 benzyloxy-8 imidazo<1,2-a>pyridine 
• 69214-22-8 8-hydroxy-imidazo<1,2-a>pyridine 
• 885276-38-0 8-benzyloxy-3-iodo-imidazo[1,2-a]pyridine 
• 943320-55-6 8-(benzyloxy)-3-((trimethylsilyl)ethynyl)imidazo[1,2-a]pyridine 
• 943320-58-9 N-(4-(methylsulfonyl)phenyl)-3-((trimethylsilyl)ethynyl)imidazo[1,2-a]pyridin-8-amine 
• 457949-09-6 6,7-dihydroimidazo[1,2-a]pyridine-8(5H)-one 
• 1219127-03-3 [2-(8-benzyloxy-imidazo[1,2-a]pyridin-3-yl)-1-(diethyl-phosphoryl)-ethyl]-phosphonic acid diethyl ester 
• 1219126-93-8 2-(8-(benzyloxy)imidazo[1,2-a]pyridin-3-yl)-1-ethane-1,1-bisphosphonic acid 
• 100592-11-8 hydrogen chloride salt of 8-hydroxy-imidazo<1,2-a>pyridine 
• 110206-61-6 3-amino-8-(phenylmethoxy)imidazo<1,2-a>pyridine 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING

Provided herein are compounds having activity against TTR related conditions, and pharmaceutically accepted salts and solvates thereof. Also provided are methods of using the compounds for inhibiting and preventing TTR aggregation and/or amyloid formation in the peripheral nerves, kidney, cardiac tissue, eye and CNS, and of treating a subject with peripheral TTR amyloidosis.

Multi-substituted amine compound and its preparation and use (by machine translation)

The invention belongs to the field of medical technology, in particular, the present invention provides the following formula I shown multi-substituted amine compound or its isomer or its pharmaceutically acceptable salt, ester, prodrug or hydrate, its pharmaceutical composition, preparation method thereof and its use in the preparation of medicine for treating aids in use. The compound or pharmaceutical composition containing the compound can be used as an inhibitor for inhibiting HIV integrase with LEDGF/p75 between protein - protein interaction and HIV integrase dimerization, then can be used for the treatment of aids. . (by machine translation)

COMPOUND, COMPOSITIONS, AND METHODS

Compounds having activity as LRRK2 inhibitors are disclosed. The compounds are of formula (I) including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Pd-Catalyzed Tandem Cyclization via C-H Arylation and Acylation for the Construction of Polycyclic Scaffolds

The first Pd-catalyzed tandem cyclization of imidazo[1,2-a]pyridines with 2-chlorobenzaldehydes through C-H arylation and acylation is presented for the efficient synthesis of novel 6H-benzo[b]imidazo[5,1,2-de]quinolizin-6-ones. The direct acylation react

METHODS AND COMPOSITIONS FOR RAF KINASE MEDIATED DISEASES

The invention discloses methods and compositions for treating or preventing RAF kinase mediated diseases or conditions by administering a compound of Formula 1: or a pharmaceutically acceptable salt, solvate or hydrate thereof, wherein the variables are defined as herein.

IMIDAZO [1, 2 -A] PYRIDINES AS JNK MODULATORS

Compounds of formula (I) modulate JNK wherein X1 and X2 are each simultaneously N or CH; X3 is CH-R2 Or N-SO2R, where R is lower alkyl; R1 is aryl or heteroaryl, substituted with 0-3 lower

IMIDAZO[1,2-α ]PYRIDINYL BISPHOSPHONATES

Novel imidazo[1,2-α]pyridinyl bisphosphonate compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating abnormal calcium and phosphate metabolism, including bone and joint diseases and other disorders.

BICYCLIC HETEROARYL COMPOUNDS

This invention relates to compounds of the general formula (I) in which the variable groups are as defined herein, and to their preparation and use.

N6-[(Imidazo[1,2-a]pyridin-3-yl)ethyl]adenosines, their 5'-uronamide analogues and pharmaceutical compositions

The present invention relates to the derivatives of the formula STR1 and their addition salts, and to their use in therapeutics as analgesics, as antihypertensives and as drugs with antiproliferative properties.

Cephalosporin compounds

A compound of the formula; STR1 wherein R0 stands for hydrogen atom, nitrogen-containing heterocyclic group, acyl group or esterified carboxyl group, Z stands for S, S→O, O or CH2, R4 stands for hydrogen atom, methoxy grou