69216-50-8

Upstream product

• 98-92-0 nicotinamide 
• 15397-15-6 1,2,3,5-tetra-O-benzoyl-2-C-methyl-β-D-ribofuranose 
• 22224-38-0 1,2,3,5-tetra-O-benzoyl-β-D-ribofuranose 

Downstream Products

• 1341-23-7 1-(β-D-ribofuranosyl)-nicotinamide 

Relevant academic research and scientific papers

Chemical synthesis method of beta-nicotinamide mononucleotide

The invention provides a chemical synthesis method of beta-nicotinamide mononucleotide. The method comprises the following steps: taking 1, 2, 3, 5-tetrabenzoyloxy-2-C-methyl-beta-D-ribofuranose and nicotinamide as initial raw materials, and sequentially carrying out condensation reaction, benzoyl protecting group removal and phosphorylation reaction, so as to prepare the beta-nicotinamide mononucleotide. The high-purity beta-nicotinamide mononucleotide can be obtained through three steps of reaction (each step of reaction does not need purification) and one step of desalination purification. The method has the advantages of easily available raw materials, short reaction route, simple post-treatment, environmental protection and high total reaction yield, and is suitable for industrial production.

Preparation method of nicotinamide ribose, reduction state and salt of nicotinamide ribose

The invention belongs to the technical field of organic synthesis. The invention discloses a preparation method of nicotinamide ribose. The method comprises the following steps: reacting an intermediate A with nicotinamide in the presence of TMSOTf to obt