692259-07-7Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of hybrid molecules containing α-methylene-γ-butyrolactones and polypyrrole minor groove binders
Baraldi, Pier Giovanni,Del Carmen Nunez, Maria,Tabrizi, Mojgan Aghazadeh,De Clercq, Erik,Balzarini, Jan,Bermejo, Jaime,Estévez, Francisco,Romagnoli, Romeo
, p. 2877 - 2886 (2007/10/03)
We have synthesized and evaluated a series of hybrids of polypyrrole minor groove binders structurally related to the natural antitumor agent distamycin A, and α-methylene-γ-butyrolactones with methyl, phenyl, and 4-substituted phenyl groups at the lacton
